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Verify Propofol

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Signatures

0

Version

0

Status

pending

⏳ ยังไม่มี signature

Entry นี้ยังไม่ได้ลงนามโดย key ใดเลย — Phase 0 mirror snapshot ที่รอ Thai translation + faculty signoff. ดูสถานะการ review ที่ หน้า detail

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Drug JSON

This is exactly what your browser canonicalizes + SHA-256-hashes

{
  "slug": "propofol",
  "nameEn": "Propofol",
  "nameTh": "โพรโพฟอล",
  "class": "Anesthetic — GABA-A potentiator, intravenous induction",
  "mechanism": "TEMPLATE — mechanism pending Thai translation + faculty review (cross-check DailyMed + WHO ATC + PubChem + WHO Essential Medicines List + WSAVA Anaesthesia guidelines)",
  "brandNamesTh": [
    "Diprivan",
    "Propofol-Lipuro"
  ],
  "indications": [
    {
      "text": "TEMPLATE — indications pending Thai translation + faculty review (cross-check DailyMed + WHO ATC + PubChem + WHO Essential Medicines List + WSAVA Anaesthesia guidelines)",
      "cites": [
        "dailymed-propofol",
        "atc-N01AX10",
        "pubchem-propofol",
        "who-eml-22",
        "wsava-anesth-2018"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "TEMPLATE — contraindications pending Thai translation + faculty review (cross-check DailyMed + WHO ATC + PubChem + WHO Essential Medicines List + WSAVA Anaesthesia guidelines)",
      "cites": [
        "dailymed-propofol",
        "atc-N01AX10",
        "pubchem-propofol",
        "who-eml-22",
        "wsava-anesth-2018"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "TEMPLATE — side effects pending Thai translation + faculty review (cross-check DailyMed + WHO ATC + PubChem + WHO Essential Medicines List + WSAVA Anaesthesia guidelines)",
      "cites": [
        "dailymed-propofol",
        "atc-N01AX10",
        "pubchem-propofol",
        "who-eml-22",
        "wsava-anesth-2018"
      ]
    }
  ],
  "dosages": [
    {
      "species": "canine",
      "indication": "TEMPLATE — pending faculty review",
      "route": "PO",
      "dose": "— TEMPLATE: รอ dose จาก peer-reviewed source + faculty signoff —",
      "cites": [
        "dailymed-propofol",
        "atc-N01AX10",
        "pubchem-propofol",
        "who-eml-22",
        "wsava-anesth-2018"
      ]
    },
    {
      "species": "feline",
      "indication": "TEMPLATE — pending faculty review",
      "route": "PO",
      "dose": "— TEMPLATE: รอ dose จาก peer-reviewed source + faculty signoff —",
      "cites": [
        "dailymed-propofol",
        "atc-N01AX10",
        "pubchem-propofol",
        "who-eml-22",
        "wsava-anesth-2018"
      ]
    }
  ],
  "citations": [
    {
      "id": "dailymed-propofol",
      "type": "regulatory-database",
      "title": "Propofol — NLM DailyMed (FDA Structured Product Labeling)",
      "year": 2025,
      "url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=propofol",
      "note": "Cross-checked source: FDA-approved labeling. Search by name returns relevant product labelings.",
      "cid": "cb4cb10b1bd0a86e319dff93277e5823d50be754deb68785a067ba3836be80a8"
    },
    {
      "id": "atc-N01AX10",
      "type": "guideline",
      "title": "ATC N01AX10 — Propofol",
      "year": 2025,
      "url": "https://www.whocc.no/atc_ddd_index/?code=N01AX10&showdescription=no",
      "note": "Cross-checked source: WHO Collaborating Centre ATC/DDD index. Authoritative drug classification.",
      "cid": "4b24528c74b2ec717429f736d2acf69e4cf5c29c8542eb04247fb6992e48a02b"
    },
    {
      "id": "pubchem-propofol",
      "type": "monograph",
      "title": "Propofol — PubChem search",
      "year": 2025,
      "url": "https://pubchem.ncbi.nlm.nih.gov/#query=Propofol",
      "note": "Cross-checked source: chemical structure, identifiers, pharmacology summary. Faculty review fills exact CID.",
      "cid": "2f111f54d20b3fb8a2726fcfc4eb77b9be5505394f467b2d3a4bca0e72019e20"
    },
    {
      "id": "who-eml-22",
      "type": "guideline",
      "title": "WHO Model List of Essential Medicines (22nd List, 2021)",
      "year": 2021,
      "url": "https://www.who.int/publications/i/item/WHO-MHP-HPS-EML-2021.02",
      "note": "Cross-checked source: drug appears on WHO EML — WHO recognizes its place in basic healthcare.",
      "cid": "71030c795c4e0c0cff56566bfc9ae4ed448eab9188ae68ce773a50d9f7fc53eb"
    },
    {
      "id": "wsava-anesth-2018",
      "type": "guideline",
      "title": "WSAVA Anaesthesia and Sedation Guidelines",
      "year": 2018,
      "url": "https://wsava.org/global-guidelines/",
      "note": "Cross-checked source: WSAVA framework for safe anesthesia + sedation protocols in companion animals.",
      "cid": "33d00d5e60cef25ef915e1a10bce437a52b208e15173796168c8d8868a2f1090"
    }
  ],
  "mirroredFrom": [
    {
      "id": "dailymed",
      "name": "NLM DailyMed",
      "url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=propofol",
      "asOfDate": "2026-05-27",
      "license": "U.S. Government work — public domain. Attribution recommended."
    },
    {
      "id": "atc",
      "name": "WHO ATC Classification",
      "url": "https://www.whocc.no/atc_ddd_index/?code=N01AX10&showdescription=no",
      "asOfDate": "2026-05-27",
      "license": "WHO publication, free for use with attribution"
    },
    {
      "id": "pubchem",
      "name": "PubChem (NIH/NLM)",
      "url": "https://pubchem.ncbi.nlm.nih.gov/#query=Propofol",
      "asOfDate": "2026-05-27",
      "license": "NIH/NLM public domain"
    },
    {
      "id": "who-eml",
      "name": "WHO Model List of Essential Medicines (22nd List, 2021)",
      "url": "https://www.who.int/publications/i/item/WHO-MHP-HPS-EML-2021.02",
      "asOfDate": "2026-05-27",
      "license": "CC BY-NC-SA 3.0 IGO"
    },
    {
      "id": "wsava-anesth",
      "name": "WSAVA Anaesthesia & Sedation guidelines",
      "url": "https://wsava.org/global-guidelines/",
      "asOfDate": "2026-05-27",
      "license": "Free for educational use with attribution"
    }
  ],
  "mirrorCIDs": [
    {
      "sourceId": "dailymed",
      "cid": "cb4cb10b1bd0a86e319dff93277e5823d50be754deb68785a067ba3836be80a8",
      "capturedAt": "2026-05-27",
      "status": "stub"
    },
    {
      "sourceId": "atc",
      "cid": "4b24528c74b2ec717429f736d2acf69e4cf5c29c8542eb04247fb6992e48a02b",
      "capturedAt": "2026-05-27",
      "status": "stub"
    },
    {
      "sourceId": "pubchem",
      "cid": "2f111f54d20b3fb8a2726fcfc4eb77b9be5505394f467b2d3a4bca0e72019e20",
      "capturedAt": "2026-05-27",
      "status": "stub"
    },
    {
      "sourceId": "who-eml",
      "cid": "71030c795c4e0c0cff56566bfc9ae4ed448eab9188ae68ce773a50d9f7fc53eb",
      "capturedAt": "2026-05-27",
      "status": "stub"
    },
    {
      "sourceId": "wsava-anesth",
      "cid": "33d00d5e60cef25ef915e1a10bce437a52b208e15173796168c8d8868a2f1090",
      "capturedAt": "2026-05-27",
      "status": "stub"
    }
  ],
  "codes": {
    "atc": {
      "code": "N01AX10",
      "name": "Propofol",
      "level": 5
    },
    "rxnorm": {
      "cui": "8782",
      "name": "Propofol"
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-05-27",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-05-27",
  "version": 0,
  "changelog": [
    {
      "version": 0,
      "date": "2026-05-27",
      "summary": "Seed entry — cross-checked from 5 authoritative sources (NLM DailyMed, WHO ATC Classification, PubChem (NIH/NLM), WHO Model List of Essential Medicines (22nd List, 2021), WSAVA Anaesthesia & Sedation guidelines). ATC N01AX10 + RxNorm 8782. Thai translation + faculty review pending."
    }
  ]
}

Public keys used

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