Verify Tylosin

Drug JSON

This is exactly what your browser canonicalizes + SHA-256-hashes

{
  "slug": "tylosin",
  "nameEn": "Tylosin",
  "nameTh": "ไทโลซิน",
  "class": "Antibiotic — macrolide (veterinary; tylosin-responsive diarrhea)",
  "mechanism": "ยาปฏิชีวนะกลุ่ม macrolide สำหรับสัตว์ จับ 50S ribosome ยับยั้งการสร้างโปรตีน; นอกจากฤทธิ์ต้านแบคทีเรียยังมีผลปรับ microbiome/anti-inflammatory ในลำไส้ จึงใช้กับ chronic colitis",
  "brandNamesTh": [
    "Tylan",
    "Tylosin"
  ],
  "indications": [
    {
      "text": "tylosin-responsive diarrhea และลำไส้ใหญ่อักเสบเรื้อรัง (chronic colitis) ในสุนัข; การติดเชื้อแบคทีเรียบางชนิด; บางครั้งใช้ใน small intestinal dysbiosis",
      "cites": [
        "petplace-tylosin",
        "merck-macrolide-b"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "รสขมมาก (ผสมอาหารหรือใส่แคปซูล); ระวังในตับบกพร่อง; โดยรวมปลอดภัย",
      "cites": [
        "petplace-tylosin"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "พบน้อย: GI upset; รสขมทำให้สัตว์ปฏิเสธอาหาร",
      "cites": [
        "petplace-tylosin"
      ]
    }
  ],
  "dosages": [
    {
      "species": "canine",
      "indication": "Tylosin-responsive diarrhea / colitis",
      "route": "PO",
      "dose": "10–20 mg/kg PO ทุก 12 ชั่วโมง (บางโปรโตคอลถึง 25 mg/kg)",
      "cites": [
        "petplace-tylosin",
        "merck-macrolide-b"
      ]
    },
    {
      "species": "feline",
      "indication": "Chronic diarrhea",
      "route": "PO",
      "dose": "10–15 mg/kg PO ทุก 12 ชั่วโมง",
      "cites": [
        "petplace-tylosin"
      ]
    }
  ],
  "citations": [
    {
      "id": "petplace-tylosin",
      "type": "monograph",
      "title": "Tylosin (Tylan) for Dogs and Cats — PetPlace",
      "url": "https://www.petplace.com/article/drug-library/drug-library/library/tylosin-tylan-for-dogs-and-cats",
      "year": 2025,
      "note": "Clinical veterinary drug reference.",
      "cid": null
    },
    {
      "id": "merck-macrolide-b",
      "type": "textbook",
      "title": "Macrolides — MSD/Merck Veterinary Manual",
      "year": 2025,
      "url": "https://www.merckvetmanual.com/pharmacology/antibacterial-agents/macrolides-azalides-and-pleuromutilins",
      "note": "Authoritative veterinary pharmacology reference. Copyrighted, cited not mirrored.",
      "cid": null
    },
    {
      "id": "wikipedia-tylosin",
      "type": "monograph",
      "title": "Tylosin — Wikipedia",
      "year": 2026,
      "url": "https://en.wikipedia.org/wiki/Tylosin",
      "note": "Tertiary cross-check for class + mechanism. CC BY-SA 4.0. Not sole authority.",
      "cid": null
    }
  ],
  "mirroredFrom": [
    {
      "id": "who-atc",
      "name": "WHO ATC/DDD Index",
      "url": "https://www.whocc.no/atc_ddd_index/",
      "asOfDate": "2026-05-30",
      "license": "WHO publication, free for use with attribution"
    }
  ],
  "mirrorCIDs": [],
  "codes": {
    "atc": {
      "code": "J01FA90",
      "name": "Tylosin (veterinary macrolide)",
      "level": 5
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-05-30",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-05-30",
  "version": 1,
  "changelog": [
    {
      "version": 1,
      "date": "2026-05-30",
      "summary": "New entry — clinical content compiled from cited authoritative sources (Merck Veterinary Manual / VIN / PetPlace / Today's Vet Practice / peer-reviewed), cross-checked. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

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