Verify Trazodone

Drug JSON

This is exactly what your browser canonicalizes + SHA-256-hashes

{
  "slug": "trazodone",
  "nameEn": "Trazodone",
  "nameTh": "ทราโซโดน",
  "class": "Behavioral — serotonin antagonist + reuptake inhibitor (SARI)",
  "mechanism": "ยา SARI ออกฤทธิ์ต้าน 5-HT2A และยับยั้งการเก็บกลับ serotonin บางส่วน ให้ความสงบและลดความวิตกกังวล; ออกฤทธิ์เร็ว ใช้ตามต้องการ (situational) ได้",
  "brandNamesTh": [
    "Desyrel"
  ],
  "indications": [
    {
      "text": "ลดความเครียด/วิตกกังวลตามสถานการณ์ (situational): พักฟื้นหลังผ่าตัด (จำกัดการเคลื่อนไหว), พบสัตวแพทย์, พายุ/เสียงดัง; ใช้เดี่ยวหรือร่วม SSRI",
      "cites": [
        "cb-trazodone"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "ห้าม/ระวังเมื่อใช้ร่วมยา serotonergic อื่น (เสี่ยง serotonin syndrome); ระวังในโรคหัวใจและตับบกพร่อง",
      "cites": [
        "cb-trazodone"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "ง่วงซึม, ความดันต่ำ, GI upset, บางครั้ง paradoxical excitement; serotonin syndrome เมื่อใช้ร่วมยา serotonergic",
      "cites": [
        "cb-trazodone"
      ]
    }
  ],
  "dosages": [
    {
      "species": "canine",
      "indication": "Situational anxiety / post-op confinement",
      "route": "PO",
      "dose": "2–12 mg/kg PO ทุก 8–24 ชั่วโมง (เริ่ม 2–3 mg/kg แล้วปรับขึ้นตามการตอบสนอง)",
      "cites": [
        "cb-trazodone"
      ]
    },
    {
      "species": "feline",
      "indication": "Pre-visit / situational anxiety",
      "route": "PO",
      "dose": "25–50 mg/ตัว PO (ปรับได้ถึง 100 mg/ตัว) ก่อนเหตุการณ์",
      "cites": [
        "cb-trazodone"
      ]
    }
  ],
  "citations": [
    {
      "id": "cb-trazodone",
      "type": "guideline",
      "title": "Trazodone for Dogs & Cats: Indications, Dosage & Effects — Clinician's Brief",
      "year": 2024,
      "url": "https://www.cliniciansbrief.com/article/trazodone-dogs-cats",
      "note": "Peer-reviewed clinical reference — dog 2–12 mg/kg, cat 25–100 mg/cat situational dosing.",
      "cid": null
    },
    {
      "id": "wikipedia-Trazodone",
      "type": "monograph",
      "title": "Trazodone — Wikipedia",
      "year": 2026,
      "url": "https://en.wikipedia.org/wiki/Trazodone",
      "note": "Tertiary cross-check for class + mechanism. CC BY-SA 4.0. Not sole authority.",
      "cid": null
    }
  ],
  "mirroredFrom": [
    {
      "id": "who-atc",
      "name": "WHO ATC/DDD Index",
      "url": "https://www.whocc.no/atc_ddd_index/",
      "asOfDate": "2026-05-27",
      "license": "WHO publication, free for use with attribution"
    }
  ],
  "mirrorCIDs": [],
  "codes": {
    "atc": {
      "code": "N06AX05",
      "name": "Trazodone",
      "level": 5
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-05-27",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-05-27",
  "version": 1,
  "changelog": [
    {
      "version": 1,
      "date": "2026-05-27",
      "summary": "New entry — clinical content compiled from cited authoritative sources (Merck Veterinary Manual / FDA-EMA labels / peer-reviewed studies), cross-checked. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

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