Verify Tetracycline

Drug JSON

This is exactly what your browser canonicalizes + SHA-256-hashes

{
  "slug": "tetracycline",
  "nameEn": "Tetracycline",
  "nameTh": "เตตราไซคลีน",
  "class": "Antibiotic — tetracycline (bacteriostatic)",
  "mechanism": "จับ 30S ribosomal subunit ยับยั้งการสร้างโปรตีนของแบคทีเรีย (bacteriostatic, broad-spectrum รวม rickettsia/mycoplasma/chlamydia); ดูดซึมลดลงเมื่อกินกับแคลเซียม/นม",
  "brandNamesTh": [
    "Tetracycline HCl",
    "Panmycin"
  ],
  "indications": [
    {
      "text": "ติดเชื้อ Rickettsia, Mycoplasma, Chlamydia, Ehrlichia (แม้ doxycycline นิยมกว่า), Leptospira (carrier), และเชื้อไวต่อยาทั่วไป",
      "cites": [
        "merck-tetracyclines-i",
        "wikipedia-tetracycline"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "⚠️ ทำให้ฟันเหลือง/กดการเจริญกระดูกในสัตว์อายุน้อยและตั้งท้อง (จับแคลเซียม); ปรับในไต/ตับบกพร่อง; ห้ามกินคู่ผลิตภัณฑ์นม/แคลเซียม/เหล็ก (ลดดูดซึม)",
      "cites": [
        "merck-tetracyclines-i"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "GI upset (อาเจียน ท้องเสีย), ฟันเปลี่ยนสีในสัตว์เด็ก, ไวแสง, esophagitis ถ้าเม็ดติดหลอดอาหาร (ตามด้วยน้ำ)",
      "cites": [
        "merck-tetracyclines-i"
      ]
    }
  ],
  "dosages": [
    {
      "species": "canine",
      "indication": "Susceptible / rickettsial infection",
      "route": "PO",
      "dose": "22 mg/kg PO ทุก 8 ชั่วโมง (ท้องว่าง)",
      "cites": [
        "merck-tetracyclines-i"
      ]
    },
    {
      "species": "feline",
      "indication": "Susceptible / mycoplasma infection",
      "route": "PO",
      "dose": "22 mg/kg PO ทุก 8 ชั่วโมง (ตามด้วยน้ำกันหลอดอาหารอักเสบ)",
      "cites": [
        "merck-tetracyclines-i"
      ]
    }
  ],
  "citations": [
    {
      "id": "merck-tetracyclines-i",
      "type": "textbook",
      "title": "Tetracyclines — MSD/Merck Veterinary Manual",
      "year": 2025,
      "url": "https://www.merckvetmanual.com/pharmacology/antibacterial-agents/tetracyclines",
      "note": "Authoritative veterinary pharmacology reference. Copyrighted, cited not mirrored.",
      "cid": null
    },
    {
      "id": "wikipedia-tetracycline",
      "type": "monograph",
      "title": "Tetracycline — Wikipedia",
      "year": 2026,
      "url": "https://en.wikipedia.org/wiki/Tetracycline",
      "note": "Tertiary cross-check for class + mechanism. CC BY-SA 4.0. Not sole authority.",
      "cid": null
    }
  ],
  "mirroredFrom": [
    {
      "id": "who-atc",
      "name": "WHO ATC/DDD Index",
      "url": "https://www.whocc.no/atc_ddd_index/",
      "asOfDate": "2026-05-30",
      "license": "WHO publication, free for use with attribution"
    }
  ],
  "mirrorCIDs": [],
  "codes": {
    "atc": {
      "code": "J01AA07",
      "name": "Tetracycline",
      "level": 5
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-05-30",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-05-30",
  "version": 1,
  "changelog": [
    {
      "version": 1,
      "date": "2026-05-30",
      "summary": "New entry — clinical content compiled from cited authoritative sources (Merck Veterinary Manual / FDA-EMA labels / ACVIM-AAHA / VIN / peer-reviewed), cross-checked. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

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