Verify Terbutaline

Drug JSON

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{
  "slug": "terbutaline",
  "nameEn": "Terbutaline",
  "nameTh": "เทอร์บูทาลีน",
  "class": "Respiratory — beta-2 adrenergic bronchodilator",
  "mechanism": "กระตุ้น β2-adrenergic receptor ทำให้กล้ามเนื้อเรียบหลอดลมคลายตัว (bronchodilation); ใช้รักษาภาวะหลอดลมหดเกร็ง โดยเฉพาะโรคหืดแมว (feline asthma) และหลอดลมอักเสบ",
  "brandNamesTh": [
    "Brethine",
    "Bricanyl"
  ],
  "indications": [
    {
      "text": "ขยายหลอดลมในภาวะหลอดลมหดเกร็ง — โรคหืดแมว (feline asthma/bronchial disease) และหลอดลมอักเสบในสุนัข; รูปแบบฉีดใช้ในภาวะหายใจลำบากเฉียบพลัน",
      "cites": [
        "tvp-feline-airway",
        "merck-airway"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "ระวังในโรคหัวใจ/arrhythmia (กระตุ้นหัวใจ), ไทรอยด์เป็นพิษ, เบาหวาน; ขนาดสูงทำให้หัวใจเต้นเร็วและสั่น",
      "cites": [
        "merck-airway"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "หัวใจเต้นเร็ว, ตัวสั่น (tremor), กระสับกระส่าย, K+ ในเลือดต่ำเมื่อขนาดสูง",
      "cites": [
        "merck-airway"
      ]
    }
  ],
  "dosages": [
    {
      "species": "canine",
      "indication": "Bronchospasm / bronchitis",
      "route": "PO",
      "dose": "0.05–0.1 mg/kg PO ทุก 8–12 ชั่วโมง; ฉีด 0.01 mg/kg SC/IM ทุก 4–6 ชม.",
      "cites": [
        "merck-airway"
      ]
    },
    {
      "species": "feline",
      "indication": "Feline asthma (incl. acute crisis)",
      "route": "SC",
      "dose": "0.01 mg/kg SC/IM (ภาวะเฉียบพลัน); PO 0.625 mg/ตัว (1/4 เม็ด 2.5 mg) ทุก 12 ชม.",
      "notes": "รูปแบบฉีดช่วยภาวะหายใจลำบากเฉียบพลันในแมวได้เร็ว",
      "cites": [
        "tvp-feline-airway",
        "merck-airway"
      ]
    }
  ],
  "citations": [
    {
      "id": "tvp-feline-airway",
      "type": "guideline",
      "title": "Treatment of Feline Lower Airway Disease — Today's Veterinary Practice",
      "url": "https://todaysveterinarypractice.com/respiratory-medicine/treatment-of-feline-lower-airway-disease/",
      "year": 2024,
      "note": "Peer-reviewed veterinary clinical practice journal.",
      "cid": null
    },
    {
      "id": "merck-airway",
      "type": "textbook",
      "title": "Systemic Treatment of Inflammatory Airway Disease in Animals — MSD/Merck Veterinary Manual",
      "year": 2025,
      "url": "https://www.merckvetmanual.com/pharmacology/systemic-pharmacotherapeutics-of-the-respiratory-system/systemic-treatment-of-inflammatory-airway-disease-in-animals",
      "note": "Authoritative veterinary pharmacology reference. Copyrighted, cited not mirrored.",
      "cid": null
    },
    {
      "id": "wikipedia-Terbutaline",
      "type": "monograph",
      "title": "Terbutaline — Wikipedia",
      "year": 2026,
      "url": "https://en.wikipedia.org/wiki/Terbutaline",
      "note": "Tertiary cross-check for class + mechanism. CC BY-SA 4.0. Not sole authority.",
      "cid": null
    }
  ],
  "mirroredFrom": [
    {
      "id": "who-atc",
      "name": "WHO ATC/DDD Index",
      "url": "https://www.whocc.no/atc_ddd_index/",
      "asOfDate": "2026-05-27",
      "license": "WHO publication, free for use with attribution"
    }
  ],
  "mirrorCIDs": [],
  "codes": {
    "atc": {
      "code": "R03AC03",
      "name": "Terbutaline",
      "level": 5
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-05-27",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-05-27",
  "version": 1,
  "changelog": [
    {
      "version": 1,
      "date": "2026-05-27",
      "summary": "New entry — clinical content compiled from cited authoritative sources (Merck Veterinary Manual / FDA-EMA labels / AAHA + ACVIM guidelines / peer-reviewed studies), cross-checked. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

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