Verify Tamsulosin

Drug JSON

This is exactly what your browser canonicalizes + SHA-256-hashes

{
  "slug": "tamsulosin",
  "nameEn": "Tamsulosin",
  "nameTh": "แทมสุโลซิน",
  "class": "Urinary — selective alpha-1A antagonist (urethral relaxant)",
  "mechanism": "alpha-1 adrenergic antagonist ที่จำเพาะต่อ subtype 1A (พบมากที่ท่อปัสสาวะ/ต่อมลูกหมาก/กระเพาะปัสสาวะ) — คลายกล้ามเนื้อเรียบหูรูดท่อปัสสาวะ ช่วยขับปัสสาวะ/นิ่ว โดยมีผลต่อความดันน้อยกว่า prazosin (uroselective)",
  "brandNamesTh": [
    "Flomax",
    "Harnal"
  ],
  "indications": [
    {
      "text": "คลายหูรูดท่อปัสสาวะใน functional urethral obstruction/urethral spasm และช่วยขับนิ่วท่อไต/ท่อปัสสาวะ (medical expulsive therapy) ในสุนัข — uroselective กว่า prazosin",
      "cites": [
        "vetdrugs-tamsulosin",
        "paper-tamsulosin"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "ระวัง hypotension (น้อยกว่า prazosin แต่ยังมี); ห้าม/ระวังใช้ร่วม alpha-blocker อื่น (prazosin/phenoxybenzamine — เสริมความดันตก); ปรับในตับบกพร่อง; ขนาดเป็น mcg/kg (เล็ก)",
      "cites": [
        "vetdrugs-tamsulosin",
        "paper-tamsulosin"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "ความดันต่ำ (uroselective จึงน้อยกว่า prazosin), ซึม/อ่อนแรง; GI upset",
      "cites": [
        "vetdrugs-tamsulosin"
      ]
    }
  ],
  "dosages": [
    {
      "species": "canine",
      "indication": "Functional urethral obstruction / ureterolith expulsion",
      "route": "PO",
      "dose": "4–6 mcg/kg PO ทุก 12–24 ชั่วโมง (≈ 0.1–0.2 mg ต่อ 10 kg; สูงสุด ~0.4 mg/วัน)",
      "cites": [
        "vetdrugs-tamsulosin",
        "paper-tamsulosin"
      ]
    }
  ],
  "citations": [
    {
      "id": "vetdrugs-tamsulosin",
      "type": "guideline",
      "title": "Tamsulosin Hydrochloride veterinary dosing — Vet Drugs List",
      "url": "https://www.vet-ebooks.com/vetdrugslist/tamsulosin-hydrochloride/",
      "year": 2025,
      "note": "Clinical veterinary drug reference.",
      "cid": null
    },
    {
      "id": "paper-tamsulosin",
      "type": "paper",
      "title": "Tamsulosin uroselectivity: prostatic/urethral retention in dogs",
      "url": "https://www.sciencedirect.com/science/article/abs/pii/S0022356524388056",
      "year": 2023,
      "note": "Peer-reviewed canine tamsulosin urethral study.",
      "cid": null
    },
    {
      "id": "wikipedia-tamsulosin",
      "type": "monograph",
      "title": "Tamsulosin — Wikipedia",
      "year": 2026,
      "url": "https://en.wikipedia.org/wiki/Tamsulosin",
      "note": "Tertiary cross-check for class + mechanism. CC BY-SA 4.0. Not sole authority.",
      "cid": null
    }
  ],
  "mirroredFrom": [
    {
      "id": "who-atc",
      "name": "WHO ATC/DDD Index",
      "url": "https://www.whocc.no/atc_ddd_index/",
      "asOfDate": "2026-05-31",
      "license": "WHO publication, free for use with attribution"
    }
  ],
  "mirrorCIDs": [],
  "codes": {
    "atc": {
      "code": "G04CA02",
      "name": "Tamsulosin",
      "level": 5
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-05-31",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-05-31",
  "version": 1,
  "changelog": [
    {
      "version": 1,
      "date": "2026-05-31",
      "summary": "New entry — clinical content compiled from cited authoritative sources (Merck Veterinary Manual / Tufts CardioRush / VCA / dvm360 / peer-reviewed), cross-checked. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

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