Verify Silver sulfadiazine

Drug JSON

This is exactly what your browser canonicalizes + SHA-256-hashes

{
  "slug": "silver-sulfadiazine",
  "nameEn": "Silver sulfadiazine",
  "nameTh": "ซิลเวอร์ซัลฟาไดอะซีน",
  "class": "Antiseptic — topical sulfonamide (burn/wound)",
  "mechanism": "topical antimicrobial — ปล่อย silver ion ที่จับ DNA แบคทีเรียยับยั้งการแบ่งตัว ร่วมกับฤทธิ์ sulfonamide; ครอบคลุมแบคทีเรียกว้าง (รวม Pseudomonas) และยีสต์ ใช้กับแผลไฟไหม้",
  "brandNamesTh": [
    "Silvadene",
    "SSD cream"
  ],
  "indications": [
    {
      "text": "ป้องกันและรักษาการติดเชื้อในแผลไฟไหม้ (ระดับ 2–3), แผลเปิด/แผลกดทับ ในสุนัข แมว และสัตว์เลี้ยงแปลกถิ่น; ครอบคลุม Pseudomonas + ยีสต์",
      "cites": [
        "vca-ssd",
        "wikipedia-silver_sulfadiazine"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "ห้ามในสัตว์แพ้ sulfonamide; ⚠️ ใช้บริเวณกว้าง/นานเสี่ยง blood dyscrasia + KCS (ตาแห้ง) ในสุนัข; ดูดซึมเล็กน้อยเมื่อทาแผลกว้าง",
      "cites": [
        "vca-ssd"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "ระคายเฉพาะที่; ใช้กว้าง/นานอาจเกิด leukopenia/blood dyscrasia, KCS; แพ้ sulfa",
      "cites": [
        "vca-ssd"
      ]
    }
  ],
  "dosages": [
    {
      "species": "canine",
      "indication": "Burn / infected wound",
      "route": "topical",
      "dose": "ทาครีม 1% ชั้นบาง ๆ บริเวณแผล วันละ 1–2 ครั้ง (หรือตามสัตวแพทย์)",
      "cites": [
        "vca-ssd"
      ]
    },
    {
      "species": "feline",
      "indication": "Burn / infected wound",
      "route": "topical",
      "dose": "ทาครีม 1% ชั้นบาง ๆ วันละ 1–2 ครั้ง",
      "cites": [
        "vca-ssd"
      ]
    }
  ],
  "citations": [
    {
      "id": "vca-ssd",
      "type": "monograph",
      "title": "Silver Sulfadiazine Topical — VCA Animal Hospitals",
      "url": "https://vcahospitals.com/know-your-pet/silver-sulfadiazine-topical",
      "year": 2025,
      "note": "Clinical veterinary drug reference.",
      "cid": null
    },
    {
      "id": "wikipedia-silver_sulfadiazine",
      "type": "monograph",
      "title": "Silver sulfadiazine — Wikipedia",
      "year": 2026,
      "url": "https://en.wikipedia.org/wiki/Silver_sulfadiazine",
      "note": "Tertiary cross-check for class + mechanism. CC BY-SA 4.0. Not sole authority.",
      "cid": null
    }
  ],
  "mirroredFrom": [
    {
      "id": "who-atc",
      "name": "WHO ATC/DDD Index",
      "url": "https://www.whocc.no/atc_ddd_index/",
      "asOfDate": "2026-05-31",
      "license": "WHO publication, free for use with attribution"
    }
  ],
  "mirrorCIDs": [],
  "codes": {
    "atc": {
      "code": "D06BA01",
      "name": "Silver sulfadiazine",
      "level": 5
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-05-31",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-05-31",
  "version": 1,
  "changelog": [
    {
      "version": 1,
      "date": "2026-05-31",
      "summary": "New entry — clinical content compiled from cited authoritative sources (Merck Veterinary Manual / FDA-EMA labels / VCA / peer-reviewed), cross-checked. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

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