Verify Selamectin

Drug JSON

This is exactly what your browser canonicalizes + SHA-256-hashes

{
  "slug": "selamectin",
  "nameEn": "Selamectin",
  "nameTh": "เซลาเมกติน",
  "class": "Antiparasitic — topical endectocide (macrocyclic lactone)",
  "mechanism": "macrocyclic lactone แบบทาผิวหนัง (spot-on) ดูดซึมเข้ากระแสเลือด ออกฤทธิ์ที่ glutamate-gated chloride channel ของปรสิต; ครอบคลุมทั้งภายนอกและภายใน (endectocide)",
  "brandNamesTh": [
    "Revolution",
    "Stronghold"
  ],
  "indications": [
    {
      "text": "ป้องกันพยาธิหนอนหัวใจ, กำจัดหมัด, ไรขี้เรื้อน (Sarcoptes, ear mites), และพยาธิตัวกลมบางชนิด ในสุนัขและแมว แบบ spot-on รายเดือน",
      "cites": [
        "tvp-selamectin",
        "fda-revolution"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "ปลอดภัยรวมถึงในสุนัขพันธุ์ที่มี MDR1 ที่ขนาดปกติ; ทาเฉพาะผิวหนัง ห้ามกิน; รอให้ขนแห้งก่อนสัมผัส",
      "cites": [
        "tvp-selamectin"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "พบน้อย: ผมร่วงเฉพาะที่บริเวณทา, ระคายเคืองผิวหนังชั่วคราว",
      "cites": [
        "tvp-selamectin"
      ]
    }
  ],
  "dosages": [
    {
      "species": "canine",
      "indication": "Flea / heartworm / mite prevention",
      "route": "topical",
      "dose": "6 mg/kg ทาผิวหนัง (spot-on) ทุกเดือน",
      "cites": [
        "fda-revolution",
        "tvp-selamectin"
      ]
    },
    {
      "species": "feline",
      "indication": "Flea / heartworm / ear mite",
      "route": "topical",
      "dose": "6 mg/kg ทาผิวหนัง (spot-on) ทุกเดือน",
      "cites": [
        "fda-revolution"
      ]
    }
  ],
  "citations": [
    {
      "id": "tvp-selamectin",
      "type": "guideline",
      "title": "Selamectin Use in Companion Animals — Today's Veterinary Practice",
      "url": "https://todaysveterinarypractice.com/pharmacology/selamectin-use-in-companion-animals/",
      "year": 2024,
      "note": "Peer-reviewed veterinary clinical practice journal.",
      "cid": null
    },
    {
      "id": "fda-revolution",
      "type": "package-insert",
      "title": "Revolution (selamectin) — FDA-approved veterinary label",
      "year": 2025,
      "url": "https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=cbcc7b04-f3ab-4f3e-a38f-dcdc313e1b8a",
      "note": "FDA-approved veterinary product label. Public FDA labeling.",
      "cid": null
    },
    {
      "id": "wikipedia-Selamectin",
      "type": "monograph",
      "title": "Selamectin — Wikipedia",
      "year": 2026,
      "url": "https://en.wikipedia.org/wiki/Selamectin",
      "note": "Tertiary cross-check for class + mechanism. CC BY-SA 4.0. Not sole authority.",
      "cid": null
    }
  ],
  "mirroredFrom": [
    {
      "id": "who-atc",
      "name": "WHO ATC/DDD Index",
      "url": "https://www.whocc.no/atc_ddd_index/",
      "asOfDate": "2026-05-27",
      "license": "WHO publication, free for use with attribution"
    }
  ],
  "mirrorCIDs": [],
  "codes": {
    "atc": {
      "code": "QP54AA05",
      "name": "Selamectin",
      "level": 5
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-05-27",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-05-27",
  "version": 1,
  "changelog": [
    {
      "version": 1,
      "date": "2026-05-27",
      "summary": "New entry — clinical content compiled from cited authoritative sources (Merck Veterinary Manual / FDA-EMA labels / peer-reviewed studies), cross-checked. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

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