Verify Robenacoxib

Drug JSON

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{
  "slug": "robenacoxib",
  "nameEn": "Robenacoxib",
  "nameTh": "โรเบนาคอกซิบ",
  "class": "NSAID — COX-2 selective coxib (tissue-selective, veterinary)",
  "mechanism": "ยา NSAID กลุ่ม coxib ยับยั้ง COX-2 อย่างจำเพาะ และมีคุณสมบัติ tissue-selective (สะสมที่บริเวณอักเสบ คงในเลือดสั้น) จึงลดผลต่อ GI/ไต; สำหรับสัตว์โดยเฉพาะ (Onsior)",
  "brandNamesTh": [
    "Onsior"
  ],
  "indications": [
    {
      "text": "ควบคุมความปวดและการอักเสบจากกล้ามเนื้อกระดูก (osteoarthritis) และความปวดหลังผ่าตัดในสุนัขและแมว; tissue-selectivity ทำให้เหมาะกับแมวที่ไวต่อ NSAID",
      "cites": [
        "petplace-robenacoxib",
        "ema-onsior"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "ห้ามใช้ในโรคไต/ตับ/หัวใจ, ขาดน้ำ, แผล GI, ความผิดปกติการแข็งตัวของเลือด; ห้ามใช้ร่วม NSAID อื่น/corticosteroid; ในแมวจำกัดระยะ 3–6 วัน",
      "cites": [
        "ema-onsior",
        "petplace-robenacoxib"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "GI (อาเจียน ท้องเสีย เบื่ออาหาร), ผลต่อไต/ตับ; โดยรวมผล GI น้อยกว่า nonselective NSAID จาก COX-2 selectivity + tissue-selectivity",
      "cites": [
        "petplace-robenacoxib"
      ]
    }
  ],
  "dosages": [
    {
      "species": "canine",
      "indication": "Osteoarthritis / post-op pain",
      "route": "PO",
      "dose": "1–2 mg/kg PO วันละครั้ง (ให้เวลาเดียวกันทุกวัน)",
      "cites": [
        "ema-onsior",
        "petplace-robenacoxib"
      ]
    },
    {
      "species": "feline",
      "indication": "Acute musculoskeletal / post-op pain",
      "route": "PO",
      "dose": "1–2 mg/kg PO วันละครั้ง (จำกัด 3–6 วันตามฉลาก)",
      "cites": [
        "ema-onsior"
      ]
    }
  ],
  "citations": [
    {
      "id": "petplace-robenacoxib",
      "type": "monograph",
      "title": "Robenacoxib (Onsior) for Dogs and Cats — PetPlace",
      "year": 2025,
      "url": "https://www.petplace.com/article/drug-library/drug-library/library/robenacoxib-onsior-for-dogs-and-cats",
      "note": "Clinical drug-library reference.",
      "cid": null
    },
    {
      "id": "ema-onsior",
      "type": "package-insert",
      "title": "Onsior (robenacoxib) — EMA/FDA veterinary label",
      "year": 2025,
      "url": "https://www.ema.europa.eu/en/medicines/veterinary/EPAR/onsior",
      "note": "FDA/EMA-approved veterinary product label. Public regulatory labeling.",
      "cid": null
    },
    {
      "id": "wikipedia-robenacoxib",
      "type": "monograph",
      "title": "Robenacoxib — Wikipedia",
      "year": 2026,
      "url": "https://en.wikipedia.org/wiki/Robenacoxib",
      "note": "Tertiary cross-check for class + mechanism. CC BY-SA 4.0. Not sole authority.",
      "cid": null
    }
  ],
  "mirroredFrom": [
    {
      "id": "who-atc",
      "name": "WHO ATC/DDD Index",
      "url": "https://www.whocc.no/atc_ddd_index/",
      "asOfDate": "2026-05-30",
      "license": "WHO publication, free for use with attribution"
    }
  ],
  "mirrorCIDs": [],
  "codes": {
    "atc": {
      "code": "QM01AH91",
      "name": "Robenacoxib (veterinary)",
      "level": 5
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-05-30",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-05-30",
  "version": 1,
  "changelog": [
    {
      "version": 1,
      "date": "2026-05-30",
      "summary": "New entry — clinical content compiled from cited authoritative sources (Merck Veterinary Manual / VCA / VSSO chemo protocols / FDA-EMA labels / Today's Vet Practice), cross-checked. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

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