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Verify Orbifloxacin

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Signatures

0

Version

1

Status

pending

⏳ ยังไม่มี signature

Entry นี้ยังไม่ได้ลงนามโดย key ใดเลย — Phase 0 mirror snapshot ที่รอ Thai translation + faculty signoff. ดูสถานะการ review ที่ หน้า detail

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Drug JSON

This is exactly what your browser canonicalizes + SHA-256-hashes

{
  "slug": "orbifloxacin",
  "nameEn": "Orbifloxacin",
  "nameTh": "ออร์บิฟลอกซาซิน",
  "class": "Fluoroquinolone antibiotic (veterinary)",
  "mechanism": "ยับยั้ง DNA gyrase/topoisomerase IV ฤทธิ์ฆ่าเชื้อ ครอบคลุมแกรมลบและแกรมบวกบางชนิด",
  "brandNamesTh": [
    "Orbax"
  ],
  "indications": [
    {
      "text": "การติดเชื้อแบคทีเรียในสุนัขและแมว (ผิวหนัง/เนื้อเยื่ออ่อน, ทางเดินปัสสาวะ)",
      "cites": [
        "dailymed-orbifloxacin",
        "plumbs"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "ระวังในสัตว์อายุน้อยช่วงกระดูกเจริญ; ⚠️ แมว — ขนาดสูงเกินเสี่ยงพิษจอตา (retinotoxicity แบบ FQ) จึงต้องคุมขนาด",
      "cites": [
        "dailymed-orbifloxacin",
        "plumbs"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "อาเจียน/ท้องเสีย; ความเสี่ยงกระดูกอ่อนในสัตว์อายุน้อย; พิษจอตาในแมวเมื่อเกินขนาด",
      "cites": [
        "plumbs",
        "wikipedia-Orbifloxacin"
      ]
    }
  ],
  "dosages": [
    {
      "species": "canine",
      "indication": "Bacterial infection",
      "route": "PO",
      "dose": "2.5–7.5 mg/kg PO วันละครั้ง",
      "cites": [
        "plumbs",
        "dailymed-orbifloxacin"
      ]
    },
    {
      "species": "feline",
      "indication": "Bacterial infection",
      "route": "PO",
      "dose": "2.5–7.5 mg/kg PO วันละครั้ง (คุมขนาดเพื่อเลี่ยงพิษจอตา)",
      "cites": [
        "plumbs"
      ]
    }
  ],
  "citations": [
    {
      "id": "atc-QJ01MA95",
      "type": "regulatory-database",
      "title": "WHO ATCvet Index — Orbifloxacin (veterinary) (QJ01MA95)",
      "year": 2026,
      "url": "https://www.whocc.no/atc_ddd_index/?code=QJ01MA95&showdescription=no",
      "note": "WHO ATCvet (Q-code) classification. Code verified against Wikipedia drug infobox. Authoritative for class + INN.",
      "cid": null
    },
    {
      "id": "dailymed-orbifloxacin",
      "type": "package-insert",
      "title": "Orbifloxacin (Orbax) — DailyMed (FDA label)",
      "year": 2026,
      "url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=orbifloxacin",
      "note": "FDA structured product label (human or veterinary). Authoritative for indications, contraindications, labeled dose.",
      "cid": null
    },
    {
      "id": "plumbs",
      "type": "textbook",
      "title": "Plumb's Veterinary Drug Handbook, 10th Edition",
      "authors": "Plumb DC",
      "year": 2023,
      "edition": "10th",
      "url": "https://www.plumbs.com/",
      "note": "Standard veterinary drug reference. Species doses cross-checked against this handbook.",
      "cid": null
    },
    {
      "id": "wikipedia-Orbifloxacin",
      "type": "monograph",
      "title": "Orbifloxacin — Wikipedia",
      "year": 2026,
      "url": "https://en.wikipedia.org/wiki/Orbifloxacin",
      "note": "Tertiary cross-check for class + mechanism + ATCvet code. CC BY-SA 4.0. Not sole authority.",
      "cid": null
    }
  ],
  "mirroredFrom": [
    {
      "id": "who-atc",
      "name": "WHO ATCvet Index",
      "url": "https://www.whocc.no/atc_ddd_index/",
      "asOfDate": "2026-06-07",
      "license": "WHO publication, free for use with attribution"
    }
  ],
  "mirrorCIDs": [],
  "codes": {
    "atc": {
      "code": "QJ01MA95",
      "name": "Orbifloxacin (veterinary)",
      "level": 5
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-06-07",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-06-07",
  "version": 1,
  "changelog": [
    {
      "version": 1,
      "date": "2026-06-07",
      "summary": "New entry — clinical content compiled from cited authoritative sources (WHO ATCvet / FDA label / Plumb’s / peer-reviewed), cross-checked. ATCvet code verified against Wikipedia infobox. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

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