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Verify Ondansetron
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Signatures
0
Version
1
Status
pending
⏳ ยังไม่มี signature
Entry นี้ยังไม่ได้ลงนามโดย key ใดเลย — Phase 0 mirror snapshot ที่รอ Thai translation + faculty signoff. ดูสถานะการ review ที่ หน้า detail
Show the raw inputs (paranoid mode)
Drug JSON
This is exactly what your browser canonicalizes + SHA-256-hashes
{
"slug": "ondansetron",
"nameEn": "Ondansetron",
"nameTh": "ออนแดนซีตรอน",
"class": "Anti-emetic — 5-HT3 receptor antagonist",
"mechanism": "ยาต้านอาเจียนกลุ่ม 5-HT3 receptor antagonist ปิดกั้นตัวรับ serotonin ที่ CTZ และทางเดินอาหาร ใช้กับอาเจียนรุนแรง โดยเฉพาะจากเคมีบำบัดและไตวาย",
"brandNamesTh": [
"Zofran"
],
"indications": [
{
"text": "อาเจียนรุนแรงที่ไม่ตอบสนองต่อยาอื่น โดยเฉพาะจากเคมีบำบัด, parvovirus enteritis, และภาวะไตวาย",
"cites": [
"acvim-gi-protectant"
]
}
],
"contraindications": [
{
"text": "ระวังในสัตว์ที่มีความผิดปกติการนำไฟฟ้าหัวใจ (QT prolongation) และตับบกพร่อง",
"cites": [
"acvim-gi-protectant"
]
}
],
"sideEffects": [
{
"text": "ท้องผูก, ง่วงซึม; โดยรวมพบผลข้างเคียงน้อย",
"cites": [
"acvim-gi-protectant"
]
}
],
"dosages": [
{
"species": "canine",
"indication": "Refractory vomiting",
"route": "IV",
"dose": "0.5–1 mg/kg PO ได้ถึง 3 ครั้ง/วัน หรือ 0.1–0.2 mg/kg IV ช้า ๆ ทุก 6–12 ชั่วโมง",
"cites": [
"acvim-gi-protectant"
]
},
{
"species": "feline",
"indication": "Refractory vomiting",
"route": "IM",
"dose": "0.22 mg/kg IM",
"cites": [
"acvim-gi-protectant"
]
}
],
"citations": [
{
"id": "acvim-gi-protectant",
"type": "guideline",
"title": "ACVIM Consensus Statement: Rational administration of gastrointestinal protectants to dogs and cats",
"authors": "Marks SL, et al.",
"year": 2018,
"url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC6271318/",
"note": "Peer-reviewed ACVIM consensus (J Vet Intern Med) — PPI/H2/sucralfate evidence + dosing. Authoritative.",
"cid": null
},
{
"id": "dailymed-ondansetron",
"type": "regulatory-database",
"title": "Ondansetron — NLM DailyMed (FDA Structured Product Labeling)",
"year": 2025,
"url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=ondansetron",
"note": "Cross-checked source: FDA-approved labeling. Search by name returns relevant product labelings.",
"cid": "414e8fa8691b9961ce7c82e83ca35c0763f1cfe53258dee45fa8476c15c48142"
},
{
"id": "atc-A04AA01",
"type": "guideline",
"title": "ATC A04AA01 — Ondansetron",
"year": 2025,
"url": "https://www.whocc.no/atc_ddd_index/?code=A04AA01&showdescription=no",
"note": "Cross-checked source: WHO Collaborating Centre ATC/DDD index. Authoritative drug classification.",
"cid": "53b9c64ef5240084ccc2a89a4b5b14d95e5ac03bb01799d552b3a6524e18fb67"
},
{
"id": "pubchem-ondansetron",
"type": "monograph",
"title": "Ondansetron — PubChem search",
"year": 2025,
"url": "https://pubchem.ncbi.nlm.nih.gov/#query=Ondansetron",
"note": "Cross-checked source: chemical structure, identifiers, pharmacology summary. Faculty review fills exact CID.",
"cid": "571110525b45795903bdbdb99aad6a014b865f8b4408fc1fb4f61642ec7a7c29"
},
{
"id": "who-eml-22",
"type": "guideline",
"title": "WHO Model List of Essential Medicines (22nd List, 2021)",
"year": 2021,
"url": "https://www.who.int/publications/i/item/WHO-MHP-HPS-EML-2021.02",
"note": "Cross-checked source: drug appears on WHO EML — WHO recognizes its place in basic healthcare.",
"cid": "71030c795c4e0c0cff56566bfc9ae4ed448eab9188ae68ce773a50d9f7fc53eb"
}
],
"mirroredFrom": [
{
"id": "dailymed",
"name": "NLM DailyMed",
"url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=ondansetron",
"asOfDate": "2026-05-27",
"license": "U.S. Government work — public domain. Attribution recommended."
},
{
"id": "atc",
"name": "WHO ATC Classification",
"url": "https://www.whocc.no/atc_ddd_index/?code=A04AA01&showdescription=no",
"asOfDate": "2026-05-27",
"license": "WHO publication, free for use with attribution"
},
{
"id": "pubchem",
"name": "PubChem (NIH/NLM)",
"url": "https://pubchem.ncbi.nlm.nih.gov/#query=Ondansetron",
"asOfDate": "2026-05-27",
"license": "NIH/NLM public domain"
},
{
"id": "who-eml",
"name": "WHO Model List of Essential Medicines (22nd List, 2021)",
"url": "https://www.who.int/publications/i/item/WHO-MHP-HPS-EML-2021.02",
"asOfDate": "2026-05-27",
"license": "CC BY-NC-SA 3.0 IGO"
}
],
"mirrorCIDs": [
{
"sourceId": "dailymed",
"cid": "414e8fa8691b9961ce7c82e83ca35c0763f1cfe53258dee45fa8476c15c48142",
"capturedAt": "2026-05-27",
"status": "stub"
},
{
"sourceId": "atc",
"cid": "53b9c64ef5240084ccc2a89a4b5b14d95e5ac03bb01799d552b3a6524e18fb67",
"capturedAt": "2026-05-27",
"status": "stub"
},
{
"sourceId": "pubchem",
"cid": "571110525b45795903bdbdb99aad6a014b865f8b4408fc1fb4f61642ec7a7c29",
"capturedAt": "2026-05-27",
"status": "stub"
},
{
"sourceId": "who-eml",
"cid": "71030c795c4e0c0cff56566bfc9ae4ed448eab9188ae68ce773a50d9f7fc53eb",
"capturedAt": "2026-05-27",
"status": "stub"
}
],
"codes": {
"atc": {
"code": "A04AA01",
"name": "Ondansetron",
"level": 5
},
"rxnorm": {
"cui": "26225",
"name": "Ondansetron"
}
},
"drafting": {
"aiAssisted": false,
"aiModel": null,
"aiPromptHash": null,
"humanReviewer": "palmzamak2547",
"humanReviewedAt": "2026-05-27",
"humanEditsRatio": null
},
"signatures": [],
"reviewedBy": null,
"lastUpdated": "2026-05-27",
"version": 1,
"changelog": [
{
"version": 0,
"date": "2026-05-27",
"summary": "Seed entry — cross-checked from 4 authoritative sources (NLM DailyMed, WHO ATC Classification, PubChem (NIH/NLM), WHO Model List of Essential Medicines (22nd List, 2021)). ATC A04AA01 + RxNorm 26225. Thai translation + faculty review pending."
},
{
"version": 1,
"date": "2026-05-27",
"summary": "Clinical content compiled from cited sources — dog 0.5–1 mg/kg PO / 0.1–0.2 mg/kg IV, cat 0.22 mg/kg verified against ACVIM consensus statement. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
}
]
}Public keys used
[]