Verify Nizatidine

Drug JSON

This is exactly what your browser canonicalizes + SHA-256-hashes

{
  "slug": "nizatidine",
  "nameEn": "Nizatidine",
  "nameTh": "ไนซาทิดีน",
  "class": "GI — H2 antagonist with prokinetic effect",
  "mechanism": "H2-receptor antagonist (ลดกรด) ที่มีฤทธิ์ prokinetic เพิ่มเติม ผ่านการยับยั้ง acetylcholinesterase เฉพาะที่ — เพิ่มการบีบตัวกระเพาะและลำไส้ใหญ่ (ต่างจาก famotidine/cimetidine ที่ไม่มีฤทธิ์นี้)",
  "brandNamesTh": [
    "Axid"
  ],
  "indications": [
    {
      "text": "ลดกรด + กระตุ้นการบีบตัว (gastric stasis, megacolon adjunct, delayed gastric emptying) ในสุนัขและแมว — H2 blocker ที่มีฤทธิ์ prokinetic",
      "cites": [
        "merck-prokinetic-b",
        "vetdrugs-nizatidine"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "ปรับขนาดในไตบกพร่อง (ขับทางไต); โดยรวมปลอดภัย; ฤทธิ์ prokinetic อาศัย cholinergic จึงระวังในภาวะที่ห้ามกระตุ้น cholinergic (เช่น GI obstruction)",
      "cites": [
        "vetdrugs-nizatidine"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "โดยรวมทนได้ดี; GI upset เล็กน้อย",
      "cites": [
        "vetdrugs-nizatidine"
      ]
    }
  ],
  "dosages": [
    {
      "species": "canine",
      "indication": "Acid suppression + prokinetic",
      "route": "PO",
      "dose": "5 mg/kg PO วันละครั้ง",
      "cites": [
        "merck-prokinetic-b",
        "vetdrugs-nizatidine"
      ]
    },
    {
      "species": "feline",
      "indication": "Acid suppression + prokinetic",
      "route": "PO",
      "dose": "2–5 mg/kg PO วันละครั้ง",
      "cites": [
        "vetdrugs-nizatidine"
      ]
    }
  ],
  "citations": [
    {
      "id": "merck-prokinetic-b",
      "type": "textbook",
      "title": "Gastrointestinal Prokinetic Drugs Used in Monogastric Animals — MSD/Merck Veterinary Manual",
      "year": 2025,
      "url": "https://www.merckvetmanual.com/pharmacology/systemic-pharmacotherapeutics-of-the-digestive-system/gastrointestinal-prokinetic-drugs-used-in-monogastric-animals",
      "note": "Authoritative veterinary pharmacology reference. Copyrighted, cited not mirrored.",
      "cid": null
    },
    {
      "id": "vetdrugs-nizatidine",
      "type": "guideline",
      "title": "Nizatidine veterinary dosing — Vet Drugs List",
      "url": "https://www.vet-ebooks.com/vetdrugslist/ranitidine/",
      "year": 2025,
      "note": "Clinical veterinary drug reference.",
      "cid": null
    },
    {
      "id": "wikipedia-nizatidine",
      "type": "monograph",
      "title": "Nizatidine — Wikipedia",
      "year": 2026,
      "url": "https://en.wikipedia.org/wiki/Nizatidine",
      "note": "Tertiary cross-check for class + mechanism. CC BY-SA 4.0. Not sole authority.",
      "cid": null
    }
  ],
  "mirroredFrom": [
    {
      "id": "who-atc",
      "name": "WHO ATC/DDD Index",
      "url": "https://www.whocc.no/atc_ddd_index/",
      "asOfDate": "2026-05-31",
      "license": "WHO publication, free for use with attribution"
    }
  ],
  "mirrorCIDs": [],
  "codes": {
    "atc": {
      "code": "A02BA04",
      "name": "Nizatidine",
      "level": 5
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-05-31",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-05-31",
  "version": 1,
  "changelog": [
    {
      "version": 1,
      "date": "2026-05-31",
      "summary": "New entry — clinical content compiled from cited authoritative sources (Merck Veterinary Manual / Tufts CardioRush / FDA labels / VCA / peer-reviewed), cross-checked. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

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