Verify Mycophenolate mofetil

Drug JSON

This is exactly what your browser canonicalizes + SHA-256-hashes

{
  "slug": "mycophenolate",
  "nameEn": "Mycophenolate mofetil",
  "nameTh": "ไมโคฟีโนเลต",
  "class": "Immunosuppressant — IMPDH inhibitor (lymphocyte-selective)",
  "mechanism": "ยับยั้งเอนไซม์ inosine monophosphate dehydrogenase (IMPDH) ขัดขวางการสร้าง purine ของ lymphocyte ที่กำลังแบ่งตัวอย่างจำเพาะ จึงกดภูมิคุ้มกันโดยกระทบเซลล์อื่นน้อย; เป็น steroid-sparing agent",
  "brandNamesTh": [
    "CellCept",
    "Myfortic"
  ],
  "indications": [
    {
      "text": "โรคภูมิคุ้มกันทำลายตนเองในสุนัข (IMHA, immune-mediated thrombocytopenia, meningoencephalitis of unknown etiology/MUE, myasthenia gravis, pemphigus) — steroid-sparing immunosuppressant",
      "cites": [
        "vetbooks-mycophenolate",
        "dvm360-mycophenolate"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "ระวังการติดเชื้อฉวยโอกาส (กดภูมิ); ข้อมูลในแมวจำกัด; ปรับลดหากเกิด GI รุนแรง",
      "cites": [
        "vetbooks-mycophenolate"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "ท้องเสีย (dose-limiting พบบ่อย), GI upset, กดไขกระดูก; เสี่ยงติดเชื้อฉวยโอกาส",
      "cites": [
        "dvm360-mycophenolate"
      ]
    }
  ],
  "dosages": [
    {
      "species": "canine",
      "indication": "Immune-mediated disease (steroid-sparing)",
      "route": "PO",
      "dose": "10–20 mg/kg PO ทุก 12 ชั่วโมง (ปรับลดหากท้องเสีย)",
      "cites": [
        "vetbooks-mycophenolate",
        "dvm360-mycophenolate"
      ]
    }
  ],
  "monitoring": [
    {
      "text": "ตรวจ CBC เป็นระยะ; เฝ้าระวัง GI side effects และการติดเชื้อ",
      "cites": [
        "dvm360-mycophenolate"
      ]
    }
  ],
  "citations": [
    {
      "id": "vetbooks-mycophenolate",
      "type": "monograph",
      "title": "Mycophenolate Dose For Dogs & Cats — Vet Drugs List",
      "url": "https://www.vet-ebooks.com/vetdrugslist/mycophenolate/",
      "year": 2025,
      "note": "Clinical veterinary drug reference.",
      "cid": null
    },
    {
      "id": "dvm360-mycophenolate",
      "type": "guideline",
      "title": "Mycophenolate mofetil as rescue therapy — dvm360",
      "url": "https://www.dvm360.com/view/mycophenolate-mofetil-rescue-therapy",
      "year": 2025,
      "note": "Clinical veterinary drug reference.",
      "cid": null
    },
    {
      "id": "wikipedia-mycophenolic_acid",
      "type": "monograph",
      "title": "Mycophenolic acid — Wikipedia",
      "year": 2026,
      "url": "https://en.wikipedia.org/wiki/Mycophenolic_acid",
      "note": "Tertiary cross-check for class + mechanism. CC BY-SA 4.0. Not sole authority.",
      "cid": null
    }
  ],
  "mirroredFrom": [
    {
      "id": "who-atc",
      "name": "WHO ATC/DDD Index",
      "url": "https://www.whocc.no/atc_ddd_index/",
      "asOfDate": "2026-05-30",
      "license": "WHO publication, free for use with attribution"
    }
  ],
  "mirrorCIDs": [],
  "codes": {
    "atc": {
      "code": "L04AA06",
      "name": "Mycophenolic acid (mycophenolate)",
      "level": 5
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-05-30",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-05-30",
  "version": 1,
  "changelog": [
    {
      "version": 1,
      "date": "2026-05-30",
      "summary": "New entry — clinical content compiled from cited authoritative sources (Merck Veterinary Manual / VIN / PetPlace / Today's Vet Practice / peer-reviewed), cross-checked. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

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