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Verify Morphine
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Signatures
0
Version
1
Status
pending
⏳ ยังไม่มี signature
Entry นี้ยังไม่ได้ลงนามโดย key ใดเลย — Phase 0 mirror snapshot ที่รอ Thai translation + faculty signoff. ดูสถานะการ review ที่ หน้า detail
Show the raw inputs (paranoid mode)
Drug JSON
This is exactly what your browser canonicalizes + SHA-256-hashes
{
"slug": "morphine",
"nameEn": "Morphine",
"nameTh": "มอร์ฟีน",
"class": "Opioid analgesic — pure mu agonist (natural opium alkaloid)",
"mechanism": "ยาแก้ปวดกลุ่ม opioid ชนิด pure mu agonist ออกฤทธิ์ที่ mu receptor ให้การระงับปวดแบบ dose-dependent (ขนาดสูง = ปวดลดมากขึ้น); ใช้กับปวดปานกลางถึงรุนแรง",
"brandNamesTh": [
"MST",
"Morphine HCl"
],
"indications": [
{
"text": "ระงับปวดปานกลางถึงรุนแรง (หลังผ่าตัด, บาดเจ็บ, มะเร็ง); ใช้ premedication และ epidural",
"cites": [
"merck-pain-mgmt",
"dvm360-analgesia"
]
}
],
"contraindications": [
{
"text": "ระวังในสัตว์ที่มีปัญหาการหายใจ, ความดันในกะโหลกสูง, ตับบกพร่อง; ฉีด IV เร็วทำให้ปล่อย histamine + ความดันตก",
"cites": [
"merck-pain-mgmt"
]
}
],
"sideEffects": [
{
"text": "กดการหายใจ, หัวใจเต้นช้า, อาเจียน/คลื่นไส้, ท้องผูก, ปัสสาวะคั่ง; ในแมวขนาดสูงอาจกระตุ้น (excitation); แก้ฤทธิ์ด้วย naloxone",
"cites": [
"merck-pain-mgmt"
]
}
],
"dosages": [
{
"species": "canine",
"indication": "Moderate–severe pain",
"route": "IM",
"dose": "0.5–2 mg/kg IM/SC หรือ IV ช้า ๆ",
"cites": [
"merck-pain-mgmt",
"dvm360-analgesia"
]
},
{
"species": "feline",
"indication": "Moderate–severe pain",
"route": "IM",
"dose": "0.1–0.3 mg/kg IM/SC (ขนาดต่ำกว่าสุนัข)",
"cites": [
"merck-pain-mgmt",
"dvm360-analgesia"
]
}
],
"citations": [
{
"id": "merck-pain-mgmt",
"type": "textbook",
"title": "Pain Management in Small Animals — MSD/Merck Veterinary Manual",
"year": 2025,
"url": "https://www.merckvetmanual.com/musculoskeletal-system/lameness-in-small-animals/pain-management-in-small-animals-with-lameness",
"note": "Merck pain-management reference — opioid dosing + mu/kappa pharmacology. Copyrighted, cited not mirrored.",
"cid": null
},
{
"id": "dvm360-analgesia",
"type": "guideline",
"title": "Analgesic drugs and sedatives (Proceedings) — dvm360",
"year": 2024,
"url": "https://www.dvm360.com/view/analgesic-drugs-and-sedatives-proceedings",
"note": "Veterinary CE proceedings — opioid dose ranges for dogs and cats. Secondary clinical reference.",
"cid": null
},
{
"id": "dailymed-morphine",
"type": "regulatory-database",
"title": "Morphine — NLM DailyMed (FDA Structured Product Labeling)",
"year": 2025,
"url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=morphine",
"note": "Cross-checked source: FDA-approved labeling. Search by name returns relevant product labelings.",
"cid": "2820d3074fb7d3dbbd67ef3cb27a743d1d338e9339c823eb738efde722cc9a8d"
},
{
"id": "atc-N02AA01",
"type": "guideline",
"title": "ATC N02AA01 — Morphine",
"year": 2025,
"url": "https://www.whocc.no/atc_ddd_index/?code=N02AA01&showdescription=no",
"note": "Cross-checked source: WHO Collaborating Centre ATC/DDD index. Authoritative drug classification.",
"cid": "054b32bc5fca1110a5ef9a76cd6062edaa6254ca9d0238c8eef3797ced142f64"
},
{
"id": "pubchem-morphine",
"type": "monograph",
"title": "Morphine — PubChem search",
"year": 2025,
"url": "https://pubchem.ncbi.nlm.nih.gov/#query=Morphine",
"note": "Cross-checked source: chemical structure, identifiers, pharmacology summary. Faculty review fills exact CID.",
"cid": "5d967fa76ba72f00783055c06f7cdfe733feb4c80093dc7d2b17af63aa0aa9b8"
},
{
"id": "who-eml-22",
"type": "guideline",
"title": "WHO Model List of Essential Medicines (22nd List, 2021)",
"year": 2021,
"url": "https://www.who.int/publications/i/item/WHO-MHP-HPS-EML-2021.02",
"note": "Cross-checked source: drug appears on WHO EML — WHO recognizes its place in basic healthcare.",
"cid": "71030c795c4e0c0cff56566bfc9ae4ed448eab9188ae68ce773a50d9f7fc53eb"
},
{
"id": "wsava-pain-2022",
"type": "guideline",
"title": "WSAVA Global Pain Council — Guidelines for Recognition, Assessment and Treatment of Pain",
"year": 2022,
"url": "https://wsava.org/global-guidelines/global-pain-council-guidelines/",
"note": "Cross-checked source: WSAVA global vet community standard for pain management.",
"cid": "4f3dfbc8262369e4ed25263fc5fd4051710cda271692dda3c34ef6bcf96b22aa"
}
],
"mirroredFrom": [
{
"id": "dailymed",
"name": "NLM DailyMed",
"url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=morphine",
"asOfDate": "2026-05-27",
"license": "U.S. Government work — public domain. Attribution recommended."
},
{
"id": "atc",
"name": "WHO ATC Classification",
"url": "https://www.whocc.no/atc_ddd_index/?code=N02AA01&showdescription=no",
"asOfDate": "2026-05-27",
"license": "WHO publication, free for use with attribution"
},
{
"id": "pubchem",
"name": "PubChem (NIH/NLM)",
"url": "https://pubchem.ncbi.nlm.nih.gov/#query=Morphine",
"asOfDate": "2026-05-27",
"license": "NIH/NLM public domain"
},
{
"id": "who-eml",
"name": "WHO Model List of Essential Medicines (22nd List, 2021)",
"url": "https://www.who.int/publications/i/item/WHO-MHP-HPS-EML-2021.02",
"asOfDate": "2026-05-27",
"license": "CC BY-NC-SA 3.0 IGO"
},
{
"id": "wsava-pain",
"name": "WSAVA Global Pain Council guidelines",
"url": "https://wsava.org/global-guidelines/global-pain-council-guidelines/",
"asOfDate": "2026-05-27",
"license": "Free for educational use with attribution"
}
],
"mirrorCIDs": [
{
"sourceId": "dailymed",
"cid": "2820d3074fb7d3dbbd67ef3cb27a743d1d338e9339c823eb738efde722cc9a8d",
"capturedAt": "2026-05-27",
"status": "stub"
},
{
"sourceId": "atc",
"cid": "054b32bc5fca1110a5ef9a76cd6062edaa6254ca9d0238c8eef3797ced142f64",
"capturedAt": "2026-05-27",
"status": "stub"
},
{
"sourceId": "pubchem",
"cid": "5d967fa76ba72f00783055c06f7cdfe733feb4c80093dc7d2b17af63aa0aa9b8",
"capturedAt": "2026-05-27",
"status": "stub"
},
{
"sourceId": "who-eml",
"cid": "71030c795c4e0c0cff56566bfc9ae4ed448eab9188ae68ce773a50d9f7fc53eb",
"capturedAt": "2026-05-27",
"status": "stub"
},
{
"sourceId": "wsava-pain",
"cid": "4f3dfbc8262369e4ed25263fc5fd4051710cda271692dda3c34ef6bcf96b22aa",
"capturedAt": "2026-05-27",
"status": "stub"
}
],
"codes": {
"atc": {
"code": "N02AA01",
"name": "Morphine",
"level": 5
},
"rxnorm": {
"cui": "7052",
"name": "Morphine"
}
},
"drafting": {
"aiAssisted": false,
"aiModel": null,
"aiPromptHash": null,
"humanReviewer": "palmzamak2547",
"humanReviewedAt": "2026-05-27",
"humanEditsRatio": null
},
"signatures": [],
"reviewedBy": null,
"lastUpdated": "2026-05-27",
"version": 1,
"changelog": [
{
"version": 0,
"date": "2026-05-27",
"summary": "Seed entry — cross-checked from 5 authoritative sources (NLM DailyMed, WHO ATC Classification, PubChem (NIH/NLM), WHO Model List of Essential Medicines (22nd List, 2021), WSAVA Global Pain Council guidelines). ATC N02AA01 + RxNorm 7052. Thai translation + faculty review pending."
},
{
"version": 1,
"date": "2026-05-27",
"summary": "Clinical content compiled from cited sources — dog 0.5–2 mg/kg, cat 0.1–0.3 mg/kg verified against Merck pain-management + dvm360. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
}
]
}Public keys used
[]