Verify Melatonin

Drug JSON

This is exactly what your browser canonicalizes + SHA-256-hashes

{
  "slug": "melatonin",
  "nameEn": "Melatonin",
  "nameTh": "เมลาโทนิน",
  "class": "Sedative — melatonin receptor agonist (sleep/anxiety/alopecia)",
  "mechanism": "ฮอร์โมนจาก pineal gland — จับ melatonin receptor ควบคุมวงจรหลับ-ตื่น (circadian) ให้ความสงบ; มีผลต่อ hair cycle จึงใช้ใน alopecia X/seasonal flank alopecia",
  "brandNamesTh": [
    "Melatonin",
    "Melatonex"
  ],
  "indications": [
    {
      "text": "ความวิตกกังวล/นอนไม่หลับ (โดยเฉพาะ cognitive dysfunction สุนัขแก่), noise phobia เสริม, และ alopecia X / seasonal flank alopecia ในสุนัข",
      "cites": [
        "petplace-melatonin",
        "paper-melatonin"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "โดยรวมปลอดภัยมาก; ⚠️ เลือกผลิตภัณฑ์ปราศจาก xylitol (เป็นพิษสุนัข); ออกฤทธิ์ช้าสำหรับ alopecia (สัปดาห์-เดือน); ระวังในเบาหวาน (อาจกระทบ insulin sensitivity เล็กน้อย)",
      "cites": [
        "petplace-melatonin"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "ง่วงซึม (ผลที่ต้องการ); โดยรวมปลอดภัย, ผลข้างเคียงน้อยมาก",
      "cites": [
        "petplace-melatonin"
      ]
    }
  ],
  "dosages": [
    {
      "species": "canine",
      "indication": "Anxiety / sleep / alopecia X",
      "route": "PO",
      "dose": "~0.1 mg/kg PO ทุก 8 ชั่วโมง; หรือตามขนาดตัว 1–6 mg/ตัว (เล็ก-ใหญ่) ทุก 8–12 ชม.; alopecia X 3–6 mg ทุก 12 ชม.",
      "cites": [
        "petplace-melatonin",
        "paper-melatonin"
      ]
    }
  ],
  "citations": [
    {
      "id": "petplace-melatonin",
      "type": "monograph",
      "title": "Melatonin (Melatonex) for Dogs and Cats — PetPlace",
      "url": "https://www.petplace.com/article/drug-library/drug-library/library/melatonin-melatonex-for-dogs-and-cats",
      "year": 2025,
      "note": "Clinical veterinary drug reference.",
      "cid": null
    },
    {
      "id": "paper-melatonin",
      "type": "paper",
      "title": "Dose-response effects of oral melatonin in male Pomeranians with alopecia X",
      "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC12070944/",
      "year": 2023,
      "note": "Peer-reviewed canine melatonin alopecia X study.",
      "cid": null
    },
    {
      "id": "wikipedia-melatonin",
      "type": "monograph",
      "title": "Melatonin — Wikipedia",
      "year": 2026,
      "url": "https://en.wikipedia.org/wiki/Melatonin",
      "note": "Tertiary cross-check for class + mechanism. CC BY-SA 4.0. Not sole authority.",
      "cid": null
    }
  ],
  "mirroredFrom": [
    {
      "id": "who-atc",
      "name": "WHO ATC/DDD Index",
      "url": "https://www.whocc.no/atc_ddd_index/",
      "asOfDate": "2026-05-31",
      "license": "WHO publication, free for use with attribution"
    }
  ],
  "mirrorCIDs": [],
  "codes": {
    "atc": {
      "code": "N05CH01",
      "name": "Melatonin",
      "level": 5
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-05-31",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-05-31",
  "version": 1,
  "changelog": [
    {
      "version": 1,
      "date": "2026-05-31",
      "summary": "New entry — clinical content compiled from cited authoritative sources (Merck Veterinary Manual / VCA / Today's Vet Practice / PetPlace / peer-reviewed), cross-checked. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

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