Verify Maropitant

Drug JSON

This is exactly what your browser canonicalizes + SHA-256-hashes

{
  "slug": "maropitant",
  "nameEn": "Maropitant",
  "nameTh": "มาโรพิแทนต์",
  "class": "Anti-emetic — NK1 receptor antagonist (veterinary)",
  "mechanism": "ยาต้านอาเจียนกลุ่ม NK1 receptor antagonist (Cerenia) ออกฤทธิ์ปิดกั้น substance P ที่ emetic center ครอบคลุมอาเจียนทั้งจากส่วนกลางและส่วนปลาย; เป็นยาสำหรับสัตว์โดยเฉพาะ",
  "brandNamesTh": [
    "Cerenia"
  ],
  "indications": [
    {
      "text": "ป้องกันและรักษาอาเจียนในสุนัขและแมว รวมถึงอาเจียนจากเมารถ (motion sickness) และจากเคมีบำบัด; ครอบคลุมกว้างกว่ายาต้านอาเจียนกลุ่มเดิม",
      "cites": [
        "fda-cerenia"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "ระวังในสัตว์ที่ตับบกพร่อง; ความปลอดภัยในลูกสัตว์อายุน้อยมากจำกัด — ดูช่วงอายุตาม label",
      "cites": [
        "fda-cerenia"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "เจ็บบริเวณที่ฉีด SC (ลดได้โดยแช่เย็นยา), น้ำลายไหล, ซึม; โดยรวมปลอดภัยสูง",
      "cites": [
        "fda-cerenia"
      ]
    }
  ],
  "dosages": [
    {
      "species": "canine",
      "indication": "Acute vomiting / motion sickness",
      "route": "SC",
      "dose": "1 mg/kg SC วันละครั้ง หรือ 2 mg/kg PO วันละครั้ง (สูงสุด 5 วันต่อเนื่อง)",
      "cites": [
        "fda-cerenia"
      ]
    },
    {
      "species": "feline",
      "indication": "Acute vomiting",
      "route": "SC",
      "dose": "1 mg/kg SC วันละครั้ง",
      "cites": [
        "fda-cerenia"
      ]
    }
  ],
  "citations": [
    {
      "id": "fda-cerenia",
      "type": "package-insert",
      "title": "Cerenia (maropitant citrate) — FDA-approved veterinary label",
      "year": 2025,
      "url": "https://www.drugs.com/pro/cerenia.html",
      "note": "FDA veterinary label — NK1 antagonist antiemetic, canine + feline dosing. Public FDA labeling.",
      "cid": null
    },
    {
      "id": "dailymed-maropitant",
      "type": "regulatory-database",
      "title": "Maropitant — NLM DailyMed (FDA Structured Product Labeling)",
      "year": 2025,
      "url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=maropitant",
      "note": "Cross-checked source: FDA-approved labeling. Search by name returns relevant product labelings.",
      "cid": "a03e1e4d4dff920a9e528c2070f0ada0052f12c36f3a331f4cba3bc473810523"
    },
    {
      "id": "atc-QA04AD90",
      "type": "guideline",
      "title": "ATC QA04AD90 — Maropitant (veterinary)",
      "year": 2025,
      "url": "https://www.whocc.no/atc_ddd_index/?code=QA04AD90&showdescription=no",
      "note": "Cross-checked source: WHO Collaborating Centre ATC/DDD index. Authoritative drug classification.",
      "cid": "40014e9e71ee641be057b1713d951d72d4e67ed6932a4978ba17683386476dea"
    },
    {
      "id": "pubchem-maropitant",
      "type": "monograph",
      "title": "Maropitant — PubChem search",
      "year": 2025,
      "url": "https://pubchem.ncbi.nlm.nih.gov/#query=Maropitant",
      "note": "Cross-checked source: chemical structure, identifiers, pharmacology summary. Faculty review fills exact CID.",
      "cid": "0bb333c9252b1a252bb02341e93b15da6ce0d0c0ad2e16d43d79c87fe69c5144"
    }
  ],
  "mirroredFrom": [
    {
      "id": "dailymed",
      "name": "NLM DailyMed",
      "url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=maropitant",
      "asOfDate": "2026-05-27",
      "license": "U.S. Government work — public domain. Attribution recommended."
    },
    {
      "id": "atc",
      "name": "WHO ATC Classification",
      "url": "https://www.whocc.no/atc_ddd_index/?code=QA04AD90&showdescription=no",
      "asOfDate": "2026-05-27",
      "license": "WHO publication, free for use with attribution"
    },
    {
      "id": "pubchem",
      "name": "PubChem (NIH/NLM)",
      "url": "https://pubchem.ncbi.nlm.nih.gov/#query=Maropitant",
      "asOfDate": "2026-05-27",
      "license": "NIH/NLM public domain"
    }
  ],
  "mirrorCIDs": [
    {
      "sourceId": "dailymed",
      "cid": "a03e1e4d4dff920a9e528c2070f0ada0052f12c36f3a331f4cba3bc473810523",
      "capturedAt": "2026-05-27",
      "status": "stub"
    },
    {
      "sourceId": "atc",
      "cid": "40014e9e71ee641be057b1713d951d72d4e67ed6932a4978ba17683386476dea",
      "capturedAt": "2026-05-27",
      "status": "stub"
    },
    {
      "sourceId": "pubchem",
      "cid": "0bb333c9252b1a252bb02341e93b15da6ce0d0c0ad2e16d43d79c87fe69c5144",
      "capturedAt": "2026-05-27",
      "status": "stub"
    }
  ],
  "codes": {
    "atc": {
      "code": "QA04AD90",
      "name": "Maropitant (veterinary)",
      "level": 5
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-05-27",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-05-27",
  "version": 1,
  "changelog": [
    {
      "version": 0,
      "date": "2026-05-27",
      "summary": "Seed entry — cross-checked from 3 authoritative sources (NLM DailyMed, WHO ATC Classification, PubChem (NIH/NLM)). ATC QA04AD90 (vet-only, no human RxNorm CUI). Thai translation + faculty review pending."
    },
    {
      "version": 1,
      "date": "2026-05-27",
      "summary": "Clinical content compiled from cited sources — dog 1 mg/kg SC or 2 mg/kg PO, cat 1 mg/kg SC verified against FDA Cerenia label. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

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