Verify Marbofloxacin

Drug JSON

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{
  "slug": "marbofloxacin",
  "nameEn": "Marbofloxacin",
  "nameTh": "มาร์โบฟลอกซาซิน",
  "class": "Antibiotic — fluoroquinolone (veterinary, once-daily)",
  "mechanism": "ยาปฏิชีวนะกลุ่ม fluoroquinolone สำหรับสัตว์ ยับยั้ง DNA gyrase/topoisomerase IV ฆ่าเชื้อ; ครอบคลุม gram-negative กว้างรวม Pseudomonas; ครึ่งชีวิตยาวให้วันละครั้ง",
  "brandNamesTh": [
    "Marbocyl",
    "Zeniquin"
  ],
  "indications": [
    {
      "text": "ติดเชื้อแบคทีเรียที่ผิวหนัง ทางเดินปัสสาวะ ทางเดินหายใจ โดยเฉพาะ gram-negative; ทางเลือกแทน enrofloxacin (ให้วันละครั้ง)",
      "cites": [
        "fda-marbofloxacin",
        "merck-marbo"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "หลีกเลี่ยงในสัตว์เล็กที่กระดูกยังเจริญไม่เต็มที่ (cartilage damage); ระวังในสัตว์ชัก; ปลอดภัยต่อจอตาแมวมากกว่า enrofloxacin แต่ยังควรระวังขนาดสูง",
      "cites": [
        "fda-marbofloxacin"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "GI upset (อาเจียน เบื่ออาหาร); ผลต่อกระดูกอ่อนในสัตว์เล็ก; เป็นพิษต่อจอตาแมวน้อยกว่า enrofloxacin",
      "cites": [
        "fda-marbofloxacin"
      ]
    }
  ],
  "dosages": [
    {
      "species": "canine",
      "indication": "Bacterial infection",
      "route": "PO",
      "dose": "2.75–5.5 mg/kg PO วันละครั้ง (อย่างน้อย 5 วัน, สูงสุด 30 วัน)",
      "cites": [
        "fda-marbofloxacin"
      ]
    },
    {
      "species": "feline",
      "indication": "Bacterial infection",
      "route": "PO",
      "dose": "2.75–5.5 mg/kg PO วันละครั้ง",
      "cites": [
        "fda-marbofloxacin"
      ]
    }
  ],
  "citations": [
    {
      "id": "fda-marbofloxacin",
      "type": "package-insert",
      "title": "Zeniquin (marbofloxacin) — FDA-approved veterinary label",
      "year": 2025,
      "url": "https://www.drugs.com/vet/zeniquin-tablets-25-mg-can.html",
      "note": "FDA-approved veterinary product label. Public FDA labeling.",
      "cid": null
    },
    {
      "id": "merck-marbo",
      "type": "textbook",
      "title": "Fluoroquinolones — MSD/Merck Veterinary Manual",
      "year": 2025,
      "url": "https://www.merckvetmanual.com/pharmacology/antibacterial-agents",
      "note": "Authoritative veterinary pharmacology reference. Copyrighted, cited not mirrored.",
      "cid": null
    },
    {
      "id": "wikipedia-Marbofloxacin",
      "type": "monograph",
      "title": "Marbofloxacin — Wikipedia",
      "year": 2026,
      "url": "https://en.wikipedia.org/wiki/Marbofloxacin",
      "note": "Tertiary cross-check for class + mechanism. CC BY-SA 4.0. Not sole authority.",
      "cid": null
    }
  ],
  "mirroredFrom": [
    {
      "id": "who-atc",
      "name": "WHO ATC/DDD Index",
      "url": "https://www.whocc.no/atc_ddd_index/",
      "asOfDate": "2026-05-27",
      "license": "WHO publication, free for use with attribution"
    }
  ],
  "mirrorCIDs": [],
  "codes": {
    "atc": {
      "code": "QJ01MA93",
      "name": "Marbofloxacin (veterinary)",
      "level": 5
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-05-27",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-05-27",
  "version": 1,
  "changelog": [
    {
      "version": 1,
      "date": "2026-05-27",
      "summary": "New entry — clinical content compiled from cited authoritative sources (Merck Veterinary Manual / FDA-EMA labels / peer-reviewed studies), cross-checked. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

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