Verify Loratadine

Drug JSON

This is exactly what your browser canonicalizes + SHA-256-hashes

{
  "slug": "loratadine",
  "nameEn": "Loratadine",
  "nameTh": "ลอราทาดีน",
  "class": "Second-generation antihistamine (H1) — non-sedating",
  "mechanism": "ปิดกั้น H1-receptor แบบไม่ผ่าน BBB จึงไม่ค่อยง่วง ใช้ลดอาการแพ้/คันเล็กน้อย (ประสิทธิภาพในสุนัข/แมวจำกัด)",
  "brandNamesTh": [
    "Clarityne"
  ],
  "indications": [
    {
      "text": "อาการแพ้/คันเล็กน้อย (allergic dermatitis adjunct) ในสุนัข — antihistamine แบบไม่ง่วง (ประสิทธิภาพแปรปรวน)",
      "cites": [
        "dailymed-loratadine",
        "plumbs"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "หลีกเลี่ยงสูตรผสม pseudoephedrine (เป็นพิษ); ประสิทธิภาพต้านคันในสัตว์ไม่แน่นอน",
      "cites": [
        "dailymed-loratadine",
        "plumbs"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "ง่วงน้อย; อาจมีอาการทางเดินอาหารเล็กน้อย",
      "cites": [
        "plumbs",
        "wikipedia-Loratadine"
      ]
    }
  ],
  "dosages": [
    {
      "species": "canine",
      "indication": "Allergic pruritus (adjunct)",
      "route": "PO",
      "dose": "~0.5–1 mg/kg PO วันละครั้ง",
      "cites": [
        "plumbs",
        "dailymed-loratadine"
      ]
    }
  ],
  "citations": [
    {
      "id": "atc-R06AX13",
      "type": "regulatory-database",
      "title": "WHO ATC/DDD Index — Loratadine (R06AX13)",
      "year": 2026,
      "url": "https://www.whocc.no/atc_ddd_index/?code=R06AX13&showdescription=no",
      "note": "WHO Anatomical Therapeutic Chemical classification. Authoritative for class + INN.",
      "cid": null
    },
    {
      "id": "dailymed-loratadine",
      "type": "package-insert",
      "title": "Loratadine — DailyMed (US FDA label)",
      "year": 2026,
      "url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=loratadine",
      "note": "US FDA structured product label. Authoritative for mechanism, indications, contraindications.",
      "cid": null
    },
    {
      "id": "plumbs",
      "type": "textbook",
      "title": "Plumb's Veterinary Drug Handbook, 10th Edition",
      "authors": "Plumb DC",
      "year": 2023,
      "edition": "10th",
      "url": "https://www.plumbs.com/",
      "note": "Standard veterinary drug reference. Species doses cross-checked against this handbook.",
      "cid": null
    },
    {
      "id": "wikipedia-Loratadine",
      "type": "monograph",
      "title": "Loratadine — Wikipedia",
      "year": 2026,
      "url": "https://en.wikipedia.org/wiki/Loratadine",
      "note": "Tertiary cross-check for class + mechanism. CC BY-SA 4.0. Not sole authority.",
      "cid": null
    }
  ],
  "mirroredFrom": [
    {
      "id": "who-atc",
      "name": "WHO ATC/DDD Index",
      "url": "https://www.whocc.no/atc_ddd_index/",
      "asOfDate": "2026-06-07",
      "license": "WHO publication, free for use with attribution"
    }
  ],
  "mirrorCIDs": [],
  "codes": {
    "atc": {
      "code": "R06AX13",
      "name": "Loratadine",
      "level": 5
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-06-07",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-06-07",
  "version": 1,
  "changelog": [
    {
      "version": 1,
      "date": "2026-06-07",
      "summary": "New entry — clinical content compiled from cited authoritative sources (WHO ATC / FDA label / Plumb’s / VSSO), cross-checked. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

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