Verify Lokivetmab

Drug JSON

This is exactly what your browser canonicalizes + SHA-256-hashes

{
  "slug": "lokivetmab",
  "nameEn": "Lokivetmab",
  "nameTh": "โลคิเวตแมบ",
  "class": "Anti-IL-31 monoclonal antibody (canine atopic dermatitis)",
  "mechanism": "โมโนโคลนอลแอนติบอดี (caninized) ที่จับและทำให้ interleukin-31 (IL-31 ซึ่งเป็นไซโตไคน์หลักของอาการคัน) เป็นกลาง ลดอาการคันในโรคผิวหนังภูมิแพ้ของสุนัขอย่างจำเพาะ",
  "brandNamesTh": [
    "Cytopoint"
  ],
  "indications": [
    {
      "text": "อาการคันจากโรคผิวหนังภูมิแพ้ (atopic/allergic dermatitis) ในสุนัข — ฉีดเดือนละครั้ง ปลอดภัยต่อระบบสูง (เป็นทางเลือก/คู่กับ oclacitinib)",
      "cites": [
        "aaha",
        "plumbs"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "เฉพาะสุนัข (caninized antibody); อาจมี anti-drug antibody ลดประสิทธิภาพในบางตัว; ไม่ใช้ในแมว",
      "cites": [
        "aaha",
        "plumbs"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "ปลอดภัยสูง (ไม่กดภูมิคุ้มกันทั่วร่าง); อาจมีอาเจียน/ซึม/ปฏิกิริยาแพ้ฉีดพบไม่บ่อย",
      "cites": [
        "plumbs",
        "wikipedia-Lokivetmab"
      ]
    }
  ],
  "dosages": [
    {
      "species": "canine",
      "indication": "Atopic dermatitis pruritus",
      "route": "SC",
      "dose": "≥ 1–2 mg/kg SC เดือนละครั้ง (ตามช่วงน้ำหนักของผลิตภัณฑ์ Cytopoint)",
      "cites": [
        "plumbs",
        "aaha"
      ]
    }
  ],
  "citations": [
    {
      "id": "atc-QD11AH91",
      "type": "regulatory-database",
      "title": "WHO ATC/ATCvet Index — Lokivetmab (QD11AH91)",
      "year": 2026,
      "url": "https://www.whocc.no/atc_ddd_index/?code=QD11AH91&showdescription=no",
      "note": "WHO ATC/ATCvet classification. Code verified against Wikipedia drug infobox. Authoritative for class + INN.",
      "cid": null
    },
    {
      "id": "aaha",
      "type": "guideline",
      "title": "2023 AAHA Management of Allergic Skin Diseases in Dogs and Cats Guidelines",
      "year": 2023,
      "url": "https://www.aaha.org/resources/2023-aaha-management-of-allergic-skin-diseases-in-dogs-and-cats-guidelines/",
      "note": "AAHA consensus guideline — atopic dermatitis therapeutics.",
      "cid": null
    },
    {
      "id": "plumbs",
      "type": "textbook",
      "title": "Plumb's Veterinary Drug Handbook, 10th Edition",
      "authors": "Plumb DC",
      "year": 2023,
      "edition": "10th",
      "url": "https://www.plumbs.com/",
      "note": "Standard veterinary drug reference. Species doses cross-checked against this handbook.",
      "cid": null
    },
    {
      "id": "wikipedia-Lokivetmab",
      "type": "monograph",
      "title": "Lokivetmab — Wikipedia",
      "year": 2026,
      "url": "https://en.wikipedia.org/wiki/Lokivetmab",
      "note": "Tertiary cross-check for class + mechanism + ATCvet code. CC BY-SA 4.0. Not sole authority.",
      "cid": null
    }
  ],
  "mirroredFrom": [
    {
      "id": "who-atc",
      "name": "WHO ATC/ATCvet Index",
      "url": "https://www.whocc.no/atc_ddd_index/",
      "asOfDate": "2026-06-07",
      "license": "WHO publication, free for use with attribution"
    }
  ],
  "mirrorCIDs": [],
  "codes": {
    "atc": {
      "code": "QD11AH91",
      "name": "Lokivetmab",
      "level": 5
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-06-07",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-06-07",
  "version": 1,
  "changelog": [
    {
      "version": 1,
      "date": "2026-06-07",
      "summary": "New entry — clinical content compiled from cited authoritative sources (WHO ATCvet / FDA label / Plumb’s / AAHA), cross-checked. ATCvet code verified against Wikipedia infobox. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

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