Verify Levamisole

Drug JSON

This is exactly what your browser canonicalizes + SHA-256-hashes

{
  "slug": "levamisole",
  "nameEn": "Levamisole",
  "nameTh": "ลีวามิโซล",
  "class": "Anthelmintic — imidazothiazole / immunomodulator",
  "mechanism": "กระตุ้น nicotinic acetylcholine receptor ของพยาธิตัวกลม ทำให้กล้ามเนื้อพยาธิเป็นอัมพาตแบบเกร็งและถูกขับออก; ขนาดต่ำมีฤทธิ์กระตุ้นภูมิคุ้มกัน (immunostimulant)",
  "brandNamesTh": [
    "Levamisole"
  ],
  "indications": [
    {
      "text": "ถ่ายพยาธิตัวกลมในทางเดินอาหารและปอดของโค แกะ สุกร; ใช้เป็น immunostimulant และจัดการ microfilaria ในสุนัข (off-label)",
      "cites": [
        "dailymed-levamisole",
        "plumbs"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "⚠️ ช่วงความปลอดภัยแคบ — เกินขนาดเกิดพิษ cholinergic (เหมือน organophosphate); ห้ามใช้ร่วมยา cholinergic อื่น; ระวังในม้า (ไวพิษ) และสัตว์ป่วยหนัก",
      "cites": [
        "dailymed-levamisole",
        "plumbs"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "อาการ cholinergic (น้ำลายไหล, สั่น, อาเจียน, ถ่าย/ปัสสาวะ), กระสับกระส่าย; เจ็บบริเวณฉีด",
      "cites": [
        "plumbs",
        "wikipedia-Levamisole"
      ]
    }
  ],
  "dosages": [
    {
      "species": "bovine",
      "indication": "Gastrointestinal & lung nematodes",
      "route": "PO",
      "dose": "7.5 mg/kg PO/SC ครั้งเดียว (ทำซ้ำตามโปรแกรมถ่ายพยาธิ)",
      "cites": [
        "plumbs",
        "dailymed-levamisole"
      ]
    },
    {
      "species": "ovine",
      "indication": "Gastrointestinal & lung nematodes",
      "route": "PO",
      "dose": "7.5 mg/kg PO ครั้งเดียว",
      "cites": [
        "plumbs"
      ]
    },
    {
      "species": "canine",
      "indication": "Immunostimulant / microfilaria (off-label)",
      "route": "PO",
      "dose": "ขนาดต่ำตามข้อบ่งใช้เฉพาะ (เช่น immunostimulant ~0.5–2 mg/kg) — ใช้ภายใต้การดูแลใกล้ชิด",
      "cites": [
        "plumbs"
      ]
    }
  ],
  "citations": [
    {
      "id": "atc-P02CE01",
      "type": "regulatory-database",
      "title": "WHO ATCvet Index — Levamisole (P02CE01)",
      "year": 2026,
      "url": "https://www.whocc.no/atc_ddd_index/?code=P02CE01&showdescription=no",
      "note": "WHO ATCvet (Q-code) classification. Authoritative for class + INN.",
      "cid": null
    },
    {
      "id": "dailymed-levamisole",
      "type": "package-insert",
      "title": "Levamisole — DailyMed (FDA label)",
      "year": 2026,
      "url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=levamisole",
      "note": "FDA structured product label (human or veterinary). Authoritative for indications, contraindications, labeled dose.",
      "cid": null
    },
    {
      "id": "plumbs",
      "type": "textbook",
      "title": "Plumb's Veterinary Drug Handbook, 10th Edition",
      "authors": "Plumb DC",
      "year": 2023,
      "edition": "10th",
      "url": "https://www.plumbs.com/",
      "note": "Standard veterinary drug reference. Species doses cross-checked against this handbook.",
      "cid": null
    },
    {
      "id": "wikipedia-Levamisole",
      "type": "monograph",
      "title": "Levamisole — Wikipedia",
      "year": 2026,
      "url": "https://en.wikipedia.org/wiki/Levamisole",
      "note": "Tertiary cross-check for class + mechanism + ATCvet code. CC BY-SA 4.0. Not sole authority.",
      "cid": null
    }
  ],
  "mirroredFrom": [
    {
      "id": "who-atc",
      "name": "WHO ATCvet Index",
      "url": "https://www.whocc.no/atc_ddd_index/",
      "asOfDate": "2026-06-07",
      "license": "WHO publication, free for use with attribution"
    }
  ],
  "mirrorCIDs": [],
  "codes": {
    "atc": {
      "code": "P02CE01",
      "name": "Levamisole",
      "level": 5
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-06-07",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-06-07",
  "version": 1,
  "changelog": [
    {
      "version": 1,
      "date": "2026-06-07",
      "summary": "New entry — clinical content compiled from cited authoritative sources (WHO ATCvet / FDA label / Plumb’s / peer-reviewed), cross-checked. ATCvet code verified against WHO/Wikipedia. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

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