Verify Imidocarb dipropionate

Drug JSON

This is exactly what your browser canonicalizes + SHA-256-hashes

{
  "slug": "imidocarb",
  "nameEn": "Imidocarb dipropionate",
  "nameTh": "อิมิโดคาร์บ ไดโพรพิโอเนต",
  "class": "Antiprotozoal — carbanilide (babesiosis/ehrlichiosis)",
  "mechanism": "อนุพันธ์ urea/carbanilide ที่รบกวนการสร้าง/ใช้ polyamine และ DNA ของโปรโตซัว ใช้รักษาและป้องกัน babesiosis รวมถึง ehrlichiosis ในสัตว์",
  "brandNamesTh": [
    "Imizol",
    "Forray"
  ],
  "indications": [
    {
      "text": "การติดเชื้อ Babesia (โรคพยาธิเม็ดเลือดจากเห็บ) และ Ehrlichia/Anaplasma ในสุนัขและโค — สำคัญมากในเขตร้อนที่มีเห็บชุกอย่างประเทศไทย",
      "cites": [
        "dailymed-imidocarb",
        "plumbs"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "ระวังในสัตว์ที่ได้รับยากลุ่ม anticholinesterase (เช่นยาฆ่าเห็บ organophosphate) เพราะเสริมฤทธิ์ cholinergic; ปรับระวังในตับ/ไตบกพร่อง; พิจารณาให้ atropine ก่อนเพื่อลดอาการ cholinergic",
      "cites": [
        "dailymed-imidocarb",
        "plumbs"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "อาการ cholinergic (น้ำลายไหล, อาเจียน, น้ำตาไหล, ปัสสาวะ/ถ่ายบ่อย), เจ็บ/บวมบริเวณฉีด, สั่น; พิษตับ/ไตเมื่อขนาดสูง",
      "cites": [
        "plumbs",
        "wikipedia-Imidocarb"
      ]
    }
  ],
  "dosages": [
    {
      "species": "canine",
      "indication": "Babesiosis / ehrlichiosis",
      "route": "IM",
      "dose": "5–6.6 mg/kg IM/SC ให้ซ้ำอีกครั้งใน 14 วัน (พิจารณา premedicate ด้วย atropine ลดอาการ cholinergic)",
      "cites": [
        "plumbs",
        "dailymed-imidocarb"
      ]
    },
    {
      "species": "bovine",
      "indication": "Babesiosis (treatment/prophylaxis)",
      "route": "SC",
      "dose": "1.2 mg/kg SC (รักษา) ถึง ~3 mg/kg (ป้องกัน) ตามฉลาก/ข้อบ่งใช้",
      "cites": [
        "plumbs"
      ]
    }
  ],
  "citations": [
    {
      "id": "atc-QP51EX01",
      "type": "regulatory-database",
      "title": "WHO ATCvet Index — Imidocarb (QP51EX01)",
      "year": 2026,
      "url": "https://www.whocc.no/atc_ddd_index/?code=QP51EX01&showdescription=no",
      "note": "WHO ATCvet (Q-code) classification. Authoritative for class + INN.",
      "cid": null
    },
    {
      "id": "dailymed-imidocarb",
      "type": "package-insert",
      "title": "Imidocarb (Imizol) — DailyMed (FDA label)",
      "year": 2026,
      "url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=imidocarb",
      "note": "FDA structured product label (human or veterinary). Authoritative for indications, contraindications, labeled dose.",
      "cid": null
    },
    {
      "id": "plumbs",
      "type": "textbook",
      "title": "Plumb's Veterinary Drug Handbook, 10th Edition",
      "authors": "Plumb DC",
      "year": 2023,
      "edition": "10th",
      "url": "https://www.plumbs.com/",
      "note": "Standard veterinary drug reference. Species doses cross-checked against this handbook.",
      "cid": null
    },
    {
      "id": "wikipedia-Imidocarb",
      "type": "monograph",
      "title": "Imidocarb — Wikipedia",
      "year": 2026,
      "url": "https://en.wikipedia.org/wiki/Imidocarb",
      "note": "Tertiary cross-check for class + mechanism + ATCvet code. CC BY-SA 4.0. Not sole authority.",
      "cid": null
    }
  ],
  "mirroredFrom": [
    {
      "id": "who-atc",
      "name": "WHO ATCvet Index",
      "url": "https://www.whocc.no/atc_ddd_index/",
      "asOfDate": "2026-06-07",
      "license": "WHO publication, free for use with attribution"
    }
  ],
  "mirrorCIDs": [],
  "codes": {
    "atc": {
      "code": "QP51EX01",
      "name": "Imidocarb",
      "level": 5
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-06-07",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-06-07",
  "version": 1,
  "changelog": [
    {
      "version": 1,
      "date": "2026-06-07",
      "summary": "New entry — clinical content compiled from cited authoritative sources (WHO ATCvet / FDA label / Plumb’s / peer-reviewed), cross-checked. ATCvet code verified against WHO/Wikipedia. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

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