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Verify Glucagon

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Signatures

0

Version

1

Status

pending

⏳ ยังไม่มี signature

Entry นี้ยังไม่ได้ลงนามโดย key ใดเลย — Phase 0 mirror snapshot ที่รอ Thai translation + faculty signoff. ดูสถานะการ review ที่ หน้า detail

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Drug JSON

This is exactly what your browser canonicalizes + SHA-256-hashes

{
  "slug": "glucagon",
  "nameEn": "Glucagon",
  "nameTh": "กลูคากอน",
  "class": "Pancreatic hormone — glucose-elevating / antidote",
  "mechanism": "กระตุ้นการสลายไกลโคเจน (glycogenolysis) และ gluconeogenesis ที่ตับ เพิ่มน้ำตาลในเลือด และมีฤทธิ์ inotrope ที่ไม่พึ่ง β-receptor (ใช้แก้พิษ β-blocker/CCB)",
  "brandNamesTh": [
    "GlucaGen"
  ],
  "indications": [
    {
      "text": "ภาวะน้ำตาลในเลือดต่ำรุนแรงดื้อต่อเดกซ์โทรส (โดยเฉพาะ insulinoma crisis) และเป็น antidote สำหรับพิษ β-blocker/calcium-channel blocker overdose",
      "cites": [
        "dailymed-glucagon",
        "plumbs"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "เนื้องอกที่ตอบสนองต่อ catecholamine (pheochromocytoma); ใช้ระยะสั้นประคับประคองระหว่างแก้สาเหตุ; ระวัง rebound hypoglycemia",
      "cites": [
        "dailymed-glucagon",
        "plumbs"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "คลื่นไส้/อาเจียน, ความดัน/หัวใจเต้นเร็ว, โพแทสเซียมต่ำ เมื่อให้ขนาดสูง/นาน",
      "cites": [
        "plumbs",
        "wikipedia-Glucagon"
      ]
    }
  ],
  "dosages": [
    {
      "species": "canine",
      "indication": "Refractory hypoglycemia (insulinoma) / BB-CCB overdose",
      "route": "IV",
      "dose": "bolus ~50 ng/kg IV แล้ว CRI 5–40 ng/kg/min ปรับตามน้ำตาลในเลือด (พิษ BB/CCB อาจใช้ขนาดสูงกว่า)",
      "cites": [
        "plumbs",
        "dailymed-glucagon"
      ]
    },
    {
      "species": "feline",
      "indication": "Refractory hypoglycemia",
      "route": "IV",
      "dose": "bolus ~50 ng/kg IV แล้ว CRI 5–40 ng/kg/min titrate",
      "cites": [
        "plumbs"
      ]
    }
  ],
  "citations": [
    {
      "id": "atc-H04AA01",
      "type": "regulatory-database",
      "title": "WHO ATC/DDD Index — Glucagon (H04AA01)",
      "year": 2026,
      "url": "https://www.whocc.no/atc_ddd_index/?code=H04AA01&showdescription=no",
      "note": "WHO Anatomical Therapeutic Chemical classification. Authoritative for class + INN.",
      "cid": null
    },
    {
      "id": "dailymed-glucagon",
      "type": "package-insert",
      "title": "Glucagon — DailyMed (FDA label)",
      "year": 2026,
      "url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=glucagon",
      "note": "FDA structured product label (human or veterinary). Authoritative for indications, contraindications, labeled use.",
      "cid": null
    },
    {
      "id": "plumbs",
      "type": "textbook",
      "title": "Plumb's Veterinary Drug Handbook, 10th Edition",
      "authors": "Plumb DC",
      "year": 2023,
      "edition": "10th",
      "url": "https://www.plumbs.com/",
      "note": "Standard veterinary drug reference. Species doses cross-checked against this handbook.",
      "cid": null
    },
    {
      "id": "wikipedia-Glucagon",
      "type": "monograph",
      "title": "Glucagon — Wikipedia",
      "year": 2026,
      "url": "https://en.wikipedia.org/wiki/Glucagon",
      "note": "Tertiary cross-check for class + mechanism + ATC code. CC BY-SA 4.0. Not sole authority.",
      "cid": null
    }
  ],
  "mirroredFrom": [
    {
      "id": "who-atc",
      "name": "WHO ATC/DDD Index",
      "url": "https://www.whocc.no/atc_ddd_index/",
      "asOfDate": "2026-06-07",
      "license": "WHO publication, free for use with attribution"
    }
  ],
  "mirrorCIDs": [],
  "codes": {
    "atc": {
      "code": "H04AA01",
      "name": "Glucagon",
      "level": 5
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-06-07",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-06-07",
  "version": 1,
  "changelog": [
    {
      "version": 1,
      "date": "2026-06-07",
      "summary": "New entry — clinical content compiled from cited authoritative sources (WHO ATC / FDA label / Plumb’s), cross-checked. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

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