Verify Gabapentin

Drug JSON

This is exactly what your browser canonicalizes + SHA-256-hashes

{
  "slug": "gabapentin",
  "nameEn": "Gabapentin",
  "nameTh": "กาบาเพนทิน",
  "class": "Anticonvulsant / analgesic — neuropathic pain + situational anxiety",
  "mechanism": "จับ α2δ subunit ของ voltage-gated calcium channel ลดการปล่อย excitatory neurotransmitter; ใช้กับปวดประสาท (neuropathic pain), เสริมยากันชัก, และลดความเครียดก่อนพบสัตวแพทย์ (โดยเฉพาะแมว)",
  "brandNamesTh": [
    "Neurontin"
  ],
  "indications": [
    {
      "text": "ปวดเรื้อรัง/ปวดประสาท (เสริม NSAID/opioid), ยากันชักเสริม, และลดความวิตกกังวลก่อนมาคลินิก/เดินทาง (situational anxiety) โดยเฉพาะในแมว",
      "cites": [
        "gabapentin-pk-review"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "ปรับลดขนาดในไตบกพร่อง (ขับทางไต); ห้ามหยุดกะทันหันเมื่อใช้กันชัก; รูปแบบน้ำของคนบางยี่ห้อมี xylitol — ห้ามใช้ในสุนัข",
      "cites": [
        "gabapentin-pk-review"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "ง่วงซึม เดินเซ (เด่นชัด โดยเฉพาะช่วงแรกหรือขนาดสูง); โดยรวมปลอดภัย",
      "cites": [
        "gabapentin-pk-review"
      ]
    }
  ],
  "dosages": [
    {
      "species": "canine",
      "indication": "Neuropathic pain / seizure adjunct",
      "route": "PO",
      "dose": "5–10 mg/kg PO ทุก 8–12 ชั่วโมง (ช่วงกว้าง 3–20 mg/kg ตามข้อบ่งใช้)",
      "cites": [
        "gabapentin-pk-review"
      ]
    },
    {
      "species": "feline",
      "indication": "Pre-visit anxiety / pain",
      "route": "PO",
      "dose": "50–100 mg/ตัว PO ก่อนเดินทาง ~2–3 ชม. (ปวด: 5–10 mg/kg ทุก 8–12 ชม.)",
      "cites": [
        "gabapentin-pk-review"
      ]
    }
  ],
  "citations": [
    {
      "id": "gabapentin-pk-review",
      "type": "paper",
      "title": "Gabapentin: Clinical Use and Pharmacokinetics in Dogs, Cats, and Horses",
      "year": 2023,
      "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC10295034/",
      "note": "Peer-reviewed PK review — gabapentin dosing ranges for dogs and cats. Authoritative.",
      "cid": null
    },
    {
      "id": "dailymed-gabapentin",
      "type": "regulatory-database",
      "title": "Gabapentin — NLM DailyMed (FDA Structured Product Labeling)",
      "year": 2025,
      "url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=gabapentin",
      "note": "Cross-checked source: FDA-approved labeling. Search by name returns relevant product labelings.",
      "cid": "5d951aa404ae629bb26824198b3dd57751949bd2b4191c0145cac984e1823f24"
    },
    {
      "id": "atc-N03AX12",
      "type": "guideline",
      "title": "ATC N03AX12 — Gabapentin",
      "year": 2025,
      "url": "https://www.whocc.no/atc_ddd_index/?code=N03AX12&showdescription=no",
      "note": "Cross-checked source: WHO Collaborating Centre ATC/DDD index. Authoritative drug classification.",
      "cid": "4324bbf28e00253c18df49cf57f841f324b0d0621689d4c829e5a44bd76dd10d"
    },
    {
      "id": "pubchem-gabapentin",
      "type": "monograph",
      "title": "Gabapentin — PubChem search",
      "year": 2025,
      "url": "https://pubchem.ncbi.nlm.nih.gov/#query=Gabapentin",
      "note": "Cross-checked source: chemical structure, identifiers, pharmacology summary. Faculty review fills exact CID.",
      "cid": "05c58f1f7afeb4c0537893af21844b6474a2d64ad1d721a27db558c824a1d5c7"
    }
  ],
  "mirroredFrom": [
    {
      "id": "dailymed",
      "name": "NLM DailyMed",
      "url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=gabapentin",
      "asOfDate": "2026-05-27",
      "license": "U.S. Government work — public domain. Attribution recommended."
    },
    {
      "id": "atc",
      "name": "WHO ATC Classification",
      "url": "https://www.whocc.no/atc_ddd_index/?code=N03AX12&showdescription=no",
      "asOfDate": "2026-05-27",
      "license": "WHO publication, free for use with attribution"
    },
    {
      "id": "pubchem",
      "name": "PubChem (NIH/NLM)",
      "url": "https://pubchem.ncbi.nlm.nih.gov/#query=Gabapentin",
      "asOfDate": "2026-05-27",
      "license": "NIH/NLM public domain"
    }
  ],
  "mirrorCIDs": [
    {
      "sourceId": "dailymed",
      "cid": "5d951aa404ae629bb26824198b3dd57751949bd2b4191c0145cac984e1823f24",
      "capturedAt": "2026-05-27",
      "status": "stub"
    },
    {
      "sourceId": "atc",
      "cid": "4324bbf28e00253c18df49cf57f841f324b0d0621689d4c829e5a44bd76dd10d",
      "capturedAt": "2026-05-27",
      "status": "stub"
    },
    {
      "sourceId": "pubchem",
      "cid": "05c58f1f7afeb4c0537893af21844b6474a2d64ad1d721a27db558c824a1d5c7",
      "capturedAt": "2026-05-27",
      "status": "stub"
    }
  ],
  "codes": {
    "atc": {
      "code": "N03AX12",
      "name": "Gabapentin",
      "level": 5
    },
    "rxnorm": {
      "cui": "4849",
      "name": "Gabapentin"
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-05-27",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-05-27",
  "version": 1,
  "changelog": [
    {
      "version": 0,
      "date": "2026-05-27",
      "summary": "Seed entry — cross-checked from 3 authoritative sources (NLM DailyMed, WHO ATC Classification, PubChem (NIH/NLM)). ATC N03AX12 + RxNorm 4849. Thai translation + faculty review pending."
    },
    {
      "version": 1,
      "date": "2026-05-27",
      "summary": "Clinical content compiled from cited sources — gabapentin 5–10 mg/kg (range 3–20) + feline pre-visit 50–100 mg/cat verified against peer-reviewed PK review (PMC10295034). Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

[]