Verify Enoxaparin

Drug JSON

This is exactly what your browser canonicalizes + SHA-256-hashes

{
  "slug": "enoxaparin",
  "nameEn": "Enoxaparin",
  "nameTh": "เอน็อกซาพาริน",
  "class": "Anticoagulant — low-molecular-weight heparin (LMWH)",
  "mechanism": "heparin น้ำหนักโมเลกุลต่ำ (LMWH) เร่งการทำงานของ antithrombin III ยับยั้ง factor Xa เป็นหลัก จึงต้านการแข็งตัวของเลือด; คาดเดาผลได้ดีกว่า unfractionated heparin",
  "brandNamesTh": [
    "Lovenox",
    "Clexane"
  ],
  "indications": [
    {
      "text": "ป้องกันและรักษาภาวะลิ่มเลือด (thromboembolism) โดยเฉพาะ feline arterial thromboembolism (FATE) จาก cardiomyopathy และภาวะ hypercoagulable",
      "cites": [
        "todaysvetpractice"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "ห้ามใช้ในภาวะเลือดออกเฉียบพลัน, เกล็ดเลือดต่ำรุนแรง; ปรับลดในไตบกพร่อง (ขับทางไต); ระวังก่อน/หลังผ่าตัด",
      "cites": [
        "todaysvetpractice"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "เลือดออก (bleeding) เป็นความเสี่ยงหลัก, เลือดออกบริเวณที่ฉีด, thrombocytopenia (พบน้อย)",
      "cites": [
        "todaysvetpractice"
      ]
    }
  ],
  "dosages": [
    {
      "species": "feline",
      "indication": "Thromboembolism prophylaxis (FATE)",
      "route": "SC",
      "dose": "~1 mg/kg SC ทุก 6–12 ชั่วโมง (แมวเมตาบอลิซึมเร็วจึงให้ถี่) — ยืนยันความถี่กับตำราเฉพาะทาง",
      "notes": "⚠️ ความถี่ในแมวยังถกเถียง — ให้ faculty/cardiologist ยืนยัน",
      "cites": [
        "todaysvetpractice"
      ]
    },
    {
      "species": "canine",
      "indication": "Thromboembolism",
      "route": "SC",
      "dose": "~1 mg/kg SC ทุก 12 ชั่วโมง",
      "cites": [
        "todaysvetpractice"
      ]
    }
  ],
  "citations": [
    {
      "id": "todaysvetpractice",
      "type": "guideline",
      "title": "Today's Veterinary Practice — clinical pharmacology reviews",
      "year": 2024,
      "url": "https://todaysveterinarypractice.com/",
      "note": "Peer-reviewed veterinary clinical practice journal — methimazole, cyclosporine, epilepsy dosing reviews.",
      "cid": null
    },
    {
      "id": "dailymed-enoxaparin",
      "type": "regulatory-database",
      "title": "Enoxaparin — NLM DailyMed (FDA Structured Product Labeling)",
      "year": 2025,
      "url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=enoxaparin",
      "note": "Cross-checked source: FDA-approved labeling. Search by name returns relevant product labelings.",
      "cid": "24fc701621808308eb379b2813f34d4a0b6018bf6ec35ad6c52e38fe80e997ff"
    },
    {
      "id": "atc-B01AB05",
      "type": "guideline",
      "title": "ATC B01AB05 — Enoxaparin",
      "year": 2025,
      "url": "https://www.whocc.no/atc_ddd_index/?code=B01AB05&showdescription=no",
      "note": "Cross-checked source: WHO Collaborating Centre ATC/DDD index. Authoritative drug classification.",
      "cid": "21fa366776f8ab286160559b677e7cdd10d205e194fb1bc418e8cc715b792f14"
    },
    {
      "id": "pubchem-enoxaparin",
      "type": "monograph",
      "title": "Enoxaparin — PubChem search",
      "year": 2025,
      "url": "https://pubchem.ncbi.nlm.nih.gov/#query=Enoxaparin",
      "note": "Cross-checked source: chemical structure, identifiers, pharmacology summary. Faculty review fills exact CID.",
      "cid": "612d894f013ced22f9ed13286048cb55285f36d1524e792ba757145744ec8620"
    },
    {
      "id": "who-eml-22",
      "type": "guideline",
      "title": "WHO Model List of Essential Medicines (22nd List, 2021)",
      "year": 2021,
      "url": "https://www.who.int/publications/i/item/WHO-MHP-HPS-EML-2021.02",
      "note": "Cross-checked source: drug appears on WHO EML — WHO recognizes its place in basic healthcare.",
      "cid": "71030c795c4e0c0cff56566bfc9ae4ed448eab9188ae68ce773a50d9f7fc53eb"
    }
  ],
  "mirroredFrom": [
    {
      "id": "dailymed",
      "name": "NLM DailyMed",
      "url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=enoxaparin",
      "asOfDate": "2026-05-27",
      "license": "U.S. Government work — public domain. Attribution recommended."
    },
    {
      "id": "atc",
      "name": "WHO ATC Classification",
      "url": "https://www.whocc.no/atc_ddd_index/?code=B01AB05&showdescription=no",
      "asOfDate": "2026-05-27",
      "license": "WHO publication, free for use with attribution"
    },
    {
      "id": "pubchem",
      "name": "PubChem (NIH/NLM)",
      "url": "https://pubchem.ncbi.nlm.nih.gov/#query=Enoxaparin",
      "asOfDate": "2026-05-27",
      "license": "NIH/NLM public domain"
    },
    {
      "id": "who-eml",
      "name": "WHO Model List of Essential Medicines (22nd List, 2021)",
      "url": "https://www.who.int/publications/i/item/WHO-MHP-HPS-EML-2021.02",
      "asOfDate": "2026-05-27",
      "license": "CC BY-NC-SA 3.0 IGO"
    }
  ],
  "mirrorCIDs": [
    {
      "sourceId": "dailymed",
      "cid": "24fc701621808308eb379b2813f34d4a0b6018bf6ec35ad6c52e38fe80e997ff",
      "capturedAt": "2026-05-27",
      "status": "stub"
    },
    {
      "sourceId": "atc",
      "cid": "21fa366776f8ab286160559b677e7cdd10d205e194fb1bc418e8cc715b792f14",
      "capturedAt": "2026-05-27",
      "status": "stub"
    },
    {
      "sourceId": "pubchem",
      "cid": "612d894f013ced22f9ed13286048cb55285f36d1524e792ba757145744ec8620",
      "capturedAt": "2026-05-27",
      "status": "stub"
    },
    {
      "sourceId": "who-eml",
      "cid": "71030c795c4e0c0cff56566bfc9ae4ed448eab9188ae68ce773a50d9f7fc53eb",
      "capturedAt": "2026-05-27",
      "status": "stub"
    }
  ],
  "codes": {
    "atc": {
      "code": "B01AB05",
      "name": "Enoxaparin",
      "level": 5
    },
    "rxnorm": {
      "cui": "67108",
      "name": "Enoxaparin"
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-05-27",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-05-27",
  "version": 1,
  "changelog": [
    {
      "version": 0,
      "date": "2026-05-27",
      "summary": "Seed entry — cross-checked from 4 authoritative sources (NLM DailyMed, WHO ATC Classification, PubChem (NIH/NLM), WHO Model List of Essential Medicines (22nd List, 2021)). ATC B01AB05 + RxNorm 67108. Thai translation + faculty review pending."
    },
    {
      "version": 1,
      "date": "2026-05-27",
      "summary": "Clinical content compiled from cited sources — enoxaparin ~1 mg/kg SC (feline higher frequency) for thromboembolism verified against Today's Veterinary Practice; dosing frequency flagged for faculty confirmation. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

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