Verify Edetate calcium disodium (CaNa2-EDTA)

Drug JSON

This is exactly what your browser canonicalizes + SHA-256-hashes

{
  "slug": "edetate-calcium-disodium",
  "nameEn": "Edetate calcium disodium (CaNa2-EDTA)",
  "nameTh": "อีดีเทต แคลเซียม ไดโซเดียม (CaNa₂-EDTA)",
  "class": "Chelating antidote — heavy metal (lead)",
  "mechanism": "จับ (chelate) ตะกั่วและโลหะหนักไดวาเลนต์ เกิดสารประกอบละลายน้ำที่ขับออกทางไต ใช้รักษาภาวะพิษตะกั่ว",
  "brandNamesTh": [
    "Calcium Disodium Versenate"
  ],
  "indications": [
    {
      "text": "ภาวะพิษตะกั่ว (lead poisoning) ในสุนัข แมว และนก",
      "cites": [
        "dailymed-edetate calcium disodium",
        "plumbs"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "ภาวะไตวาย/ปัสสาวะไม่ออก (anuria); ⚠️ ห้ามใช้ disodium EDTA (ไม่มี Ca) แทน — ทำให้แคลเซียมในเลือดต่ำถึงชีวิต; ให้สารน้ำเพียงพอ + เจือจางก่อนให้",
      "cites": [
        "dailymed-edetate calcium disodium",
        "plumbs"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "พิษต่อไต (renal tubular necrosis), อาเจียน/ท้องเสีย, ขาด zinc เมื่อใช้นาน; เจ็บบริเวณฉีด SC",
      "cites": [
        "plumbs",
        "wikipedia-Sodium_calcium_edetate"
      ]
    }
  ],
  "dosages": [
    {
      "species": "canine",
      "indication": "Lead poisoning",
      "route": "SC",
      "dose": "25 mg/kg SC/IV (เจือจาง) ทุก 6 ชั่วโมง (รวม ~100 mg/kg/วัน) นาน 2–5 วัน แล้วหยุดประเมิน — ให้สารน้ำเพียงพอ",
      "cites": [
        "plumbs",
        "dailymed-edetate calcium disodium"
      ]
    },
    {
      "species": "feline",
      "indication": "Lead poisoning",
      "route": "SC",
      "dose": "25 mg/kg SC (เจือจาง) ทุก 6 ชั่วโมง นาน 2–5 วัน",
      "cites": [
        "plumbs"
      ]
    }
  ],
  "citations": [
    {
      "id": "atc-V03AB03",
      "type": "regulatory-database",
      "title": "WHO ATC/DDD Index — Sodium calcium edetate (V03AB03)",
      "year": 2026,
      "url": "https://www.whocc.no/atc_ddd_index/?code=V03AB03&showdescription=no",
      "note": "WHO Anatomical Therapeutic Chemical classification. Authoritative for class + INN.",
      "cid": null
    },
    {
      "id": "dailymed-edetate calcium disodium",
      "type": "package-insert",
      "title": "Edetate calcium disodium — DailyMed (US FDA label)",
      "year": 2026,
      "url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=edetate%20calcium%20disodium",
      "note": "US FDA structured product label. Authoritative for indications, contraindications, labeled use.",
      "cid": null
    },
    {
      "id": "plumbs",
      "type": "textbook",
      "title": "Plumb's Veterinary Drug Handbook, 10th Edition",
      "authors": "Plumb DC",
      "year": 2023,
      "edition": "10th",
      "url": "https://www.plumbs.com/",
      "note": "Standard veterinary drug reference. Species doses cross-checked against this handbook.",
      "cid": null
    },
    {
      "id": "wikipedia-Sodium_calcium_edetate",
      "type": "monograph",
      "title": "Sodium calcium edetate — Wikipedia",
      "year": 2026,
      "url": "https://en.wikipedia.org/wiki/Sodium_calcium_edetate",
      "note": "Tertiary cross-check for class + mechanism. CC BY-SA 4.0. Not sole authority.",
      "cid": null
    }
  ],
  "mirroredFrom": [
    {
      "id": "who-atc",
      "name": "WHO ATC/DDD Index",
      "url": "https://www.whocc.no/atc_ddd_index/",
      "asOfDate": "2026-06-07",
      "license": "WHO publication, free for use with attribution"
    }
  ],
  "mirrorCIDs": [],
  "codes": {
    "atc": {
      "code": "V03AB03",
      "name": "Sodium calcium edetate",
      "level": 5
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-06-07",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-06-07",
  "version": 1,
  "changelog": [
    {
      "version": 1,
      "date": "2026-06-07",
      "summary": "New entry — clinical content compiled from cited authoritative sources (WHO ATC / FDA label / Plumb’s / peer-reviewed), cross-checked. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

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