Verify Dopamine

Drug JSON

This is exactly what your browser canonicalizes + SHA-256-hashes

{
  "slug": "dopamine",
  "nameEn": "Dopamine",
  "nameTh": "โดพามีน",
  "class": "Emergency — dopaminergic/adrenergic vasopressor (CRI)",
  "mechanism": "กระตุ้น dopaminergic และ adrenergic receptor แบบ dose-dependent: ขนาดต่ำเพิ่ม renal/mesenteric flow, ขนาดกลางเพิ่ม inotropy (β1), ขนาดสูง vasoconstriction (α); ให้แบบ CRI เท่านั้น",
  "brandNamesTh": [
    "Intropin"
  ],
  "indications": [
    {
      "text": "ภาวะความดันต่ำ/ช็อกที่ไม่ตอบสนองต่อสารน้ำ (hypotension, shock), รองรับการไหลเวียนระหว่างวางยาสลบ; ให้แบบ CRI ปรับขนาดตามความดัน",
      "cites": [
        "merck-dopamine",
        "tvp-cri"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "ให้ทาง CRI ผ่าน infusion pump เท่านั้น; ระวัง tachyarrhythmia; การรั่วออกนอกหลอดเลือด (extravasation) ทำให้เนื้อตาย",
      "cites": [
        "merck-dopamine"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "หัวใจเต้นเร็ว/arrhythmia, ความดันสูงเกิน, เนื้อตายจากการรั่วออกนอกหลอดเลือด; ปรับขนาดช้า ๆ ขณะเฝ้าระวัง",
      "cites": [
        "merck-dopamine"
      ]
    }
  ],
  "dosages": [
    {
      "species": "canine",
      "indication": "Hypotension / shock (CRI)",
      "route": "IV",
      "dose": "1–15 mcg/kg/min CRI ปรับตามการตอบสนอง (ความดัน, HR)",
      "cites": [
        "merck-dopamine",
        "tvp-cri"
      ]
    },
    {
      "species": "feline",
      "indication": "Hypotension / shock (CRI)",
      "route": "IV",
      "dose": "1–15 mcg/kg/min CRI",
      "cites": [
        "merck-dopamine"
      ]
    }
  ],
  "citations": [
    {
      "id": "merck-dopamine",
      "type": "textbook",
      "title": "Positive Inotropes — MSD/Merck Veterinary Manual",
      "year": 2025,
      "url": "https://www.merckvetmanual.com/pharmacology/systemic-pharmacotherapeutics-of-the-cardiovascular-system/positive-inotropes-for-use-in-animals",
      "note": "Authoritative veterinary pharmacology reference. Copyrighted, cited not mirrored.",
      "cid": null
    },
    {
      "id": "tvp-cri",
      "type": "guideline",
      "title": "CRI use for anesthesia and analgesia — Today's Veterinary Practice",
      "url": "https://www.dvm360.com/view/cri-use-anesthesia-and-analgesia-proceedings",
      "year": 2024,
      "note": "Peer-reviewed veterinary clinical practice journal.",
      "cid": null
    },
    {
      "id": "wikipedia-Dopamine",
      "type": "monograph",
      "title": "Dopamine — Wikipedia",
      "year": 2026,
      "url": "https://en.wikipedia.org/wiki/Dopamine",
      "note": "Tertiary cross-check for class + mechanism. CC BY-SA 4.0. Not sole authority.",
      "cid": null
    }
  ],
  "mirroredFrom": [
    {
      "id": "who-atc",
      "name": "WHO ATC/DDD Index",
      "url": "https://www.whocc.no/atc_ddd_index/",
      "asOfDate": "2026-05-27",
      "license": "WHO publication, free for use with attribution"
    }
  ],
  "mirrorCIDs": [],
  "codes": {
    "atc": {
      "code": "C01CA04",
      "name": "Dopamine",
      "level": 5
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-05-27",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-05-27",
  "version": 1,
  "changelog": [
    {
      "version": 1,
      "date": "2026-05-27",
      "summary": "New entry — clinical content compiled from cited authoritative sources (RECOVER 2024 / BSAVA / Merck / AAHA / ACVIM / peer-reviewed), cross-checked. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

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