Verify Docusate sodium

Drug JSON

This is exactly what your browser canonicalizes + SHA-256-hashes

{
  "slug": "docusate",
  "nameEn": "Docusate sodium",
  "nameTh": "โดคูเสต โซเดียม",
  "class": "GI — stool softener (emollient laxative)",
  "mechanism": "surfactant (emollient laxative) — ลดแรงตึงผิว ทำให้น้ำและไขมันแทรกเข้าก้อนอุจจาระ จึงนิ่มลงและขับง่าย; ใช้กับท้องผูก/megacolon",
  "brandNamesTh": [
    "Colace",
    "Docusate"
  ],
  "indications": [
    {
      "text": "ท้องผูก, อุจจาระแข็ง, ป้องกันการเบ่งหลังผ่าตัด/ในโรค megacolon ในสุนัขและแมว — ทำให้อุจจาระนิ่ม",
      "cites": [
        "petplace-docusate",
        "merck-constipation"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "ต้องให้น้ำเพียงพอ (ทำงานโดยดึงน้ำเข้าอุจจาระ); ห้ามในภาวะลำไส้อุดตัน/ขาดน้ำ; เลี่ยงให้ร่วม mineral oil (เพิ่มการดูดซึม mineral oil); ระยะสั้น",
      "cites": [
        "petplace-docusate"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "โดยรวมปลอดภัย; ปวดเกร็งท้อง/ท้องเสียถ้าขนาดสูง; ขาดน้ำถ้าไม่ดื่มน้ำพอ",
      "cites": [
        "petplace-docusate"
      ]
    }
  ],
  "dosages": [
    {
      "species": "canine",
      "indication": "Constipation / stool softening",
      "route": "PO",
      "dose": "สุนัขเล็ก 25–50 mg/ตัว, กลาง 50–100 mg, ใหญ่ 100–200 mg PO ทุก 12–24 ชั่วโมง",
      "cites": [
        "petplace-docusate",
        "merck-constipation"
      ]
    },
    {
      "species": "feline",
      "indication": "Constipation / megacolon",
      "route": "PO",
      "dose": "50 mg/ตัว PO ทุก 12–24 ชั่วโมง",
      "cites": [
        "petplace-docusate"
      ]
    }
  ],
  "citations": [
    {
      "id": "petplace-docusate",
      "type": "monograph",
      "title": "Docusate (Colace) for Dogs and Cats — PetPlace",
      "url": "https://www.petplace.com/article/drug-library/drug-library/library/docusate-colace-for-dogs-and-cats",
      "year": 2025,
      "note": "Clinical veterinary drug reference.",
      "cid": null
    },
    {
      "id": "merck-constipation",
      "type": "textbook",
      "title": "Constipation, Obstipation, and Megacolon in Small Animals — MSD/Merck Veterinary Manual",
      "year": 2025,
      "url": "https://www.merckvetmanual.com/digestive-system/diseases-of-the-stomach-and-intestines-in-small-animals/constipation-and-obstipation-in-small-animals",
      "note": "Authoritative veterinary pharmacology reference. Copyrighted, cited not mirrored.",
      "cid": null
    },
    {
      "id": "wikipedia-docusate",
      "type": "monograph",
      "title": "Docusate — Wikipedia",
      "year": 2026,
      "url": "https://en.wikipedia.org/wiki/Docusate",
      "note": "Tertiary cross-check for class + mechanism. CC BY-SA 4.0. Not sole authority.",
      "cid": null
    }
  ],
  "mirroredFrom": [
    {
      "id": "who-atc",
      "name": "WHO ATC/DDD Index",
      "url": "https://www.whocc.no/atc_ddd_index/",
      "asOfDate": "2026-05-31",
      "license": "WHO publication, free for use with attribution"
    }
  ],
  "mirrorCIDs": [],
  "codes": {
    "atc": {
      "code": "A06AA02",
      "name": "Docusate sodium",
      "level": 5
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-05-31",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-05-31",
  "version": 1,
  "changelog": [
    {
      "version": 1,
      "date": "2026-05-31",
      "summary": "New entry — clinical content compiled from cited authoritative sources (Merck Veterinary Manual / VCA / Today's Vet Practice / PetPlace / peer-reviewed), cross-checked. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

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