Verify Cyproheptadine

Drug JSON

This is exactly what your browser canonicalizes + SHA-256-hashes

{
  "slug": "cyproheptadine",
  "nameEn": "Cyproheptadine",
  "nameTh": "ไซโปรเฮปตาดีน",
  "class": "Antihistamine — first-generation H1 + serotonin antagonist (appetite stimulant)",
  "mechanism": "ยาต้าน H1 รุ่นแรกที่มีฤทธิ์ต้าน serotonin (5-HT) ด้วย จึงกระตุ้นความอยากอาหารและใช้ในโรคหืดแมว; ฤทธิ์ anticholinergic ทำให้ง่วง",
  "brandNamesTh": [
    "Periactin"
  ],
  "indications": [
    {
      "text": "กระตุ้นความอยากอาหารในแมว (appetite stimulant), เสริมการจัดการโรคหืดแมว (feline asthma), และต้านอาการแพ้; ทางเลือกกระตุ้นอาหารร่วม/แทน mirtazapine",
      "cites": [
        "merck-cyproheptadine"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "ระวังในต้อหิน, ปัสสาวะคั่ง, โรคหัวใจ (ฤทธิ์ anticholinergic); ทำให้ง่วงและบางครั้งกระตุ้น",
      "cites": [
        "merck-cyproheptadine"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "ง่วงซึม, ปากแห้ง, บางครั้งกระตุ้น (excitement) ในแมว; กระตุ้นอาหารมาก",
      "cites": [
        "merck-cyproheptadine"
      ]
    }
  ],
  "dosages": [
    {
      "species": "feline",
      "indication": "Appetite stimulation / asthma adjunct",
      "route": "PO",
      "dose": "1–2 mg/ตัว PO ทุก 12 ชั่วโมง",
      "cites": [
        "merck-cyproheptadine"
      ]
    },
    {
      "species": "canine",
      "indication": "Antihistamine / appetite",
      "route": "PO",
      "dose": "0.3–2 mg/kg PO ทุก 8–12 ชั่วโมง",
      "cites": [
        "merck-cyproheptadine"
      ]
    }
  ],
  "citations": [
    {
      "id": "merck-cyproheptadine",
      "type": "textbook",
      "title": "Antihistamines / Respiratory drugs — MSD/Merck Veterinary Manual",
      "year": 2025,
      "url": "https://www.merckvetmanual.com/pharmacology/systemic-pharmacotherapeutics-of-the-respiratory-system",
      "note": "Authoritative veterinary pharmacology reference. Copyrighted, cited not mirrored.",
      "cid": null
    },
    {
      "id": "wikipedia-Cyproheptadine",
      "type": "monograph",
      "title": "Cyproheptadine — Wikipedia",
      "year": 2026,
      "url": "https://en.wikipedia.org/wiki/Cyproheptadine",
      "note": "Tertiary cross-check for class + mechanism. CC BY-SA 4.0. Not sole authority.",
      "cid": null
    }
  ],
  "mirroredFrom": [
    {
      "id": "who-atc",
      "name": "WHO ATC/DDD Index",
      "url": "https://www.whocc.no/atc_ddd_index/",
      "asOfDate": "2026-05-27",
      "license": "WHO publication, free for use with attribution"
    }
  ],
  "mirrorCIDs": [],
  "codes": {
    "atc": {
      "code": "R06AX02",
      "name": "Cyproheptadine",
      "level": 5
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-05-27",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-05-27",
  "version": 1,
  "changelog": [
    {
      "version": 1,
      "date": "2026-05-27",
      "summary": "New entry — clinical content compiled from cited authoritative sources (Merck Veterinary Manual / FDA-EMA labels / peer-reviewed studies), cross-checked. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

[]