Verify Codeine

Drug JSON

This is exactly what your browser canonicalizes + SHA-256-hashes

{
  "slug": "codeine",
  "nameEn": "Codeine",
  "nameTh": "โคเดอีน",
  "class": "Antitussives & expectorants — opioid (antitussive + mild analgesic)",
  "mechanism": "opioid อ่อน — กดศูนย์ไอที่ medulla (antitussive ใกล้เคียง morphine) และระงับปวดเล็กน้อย (~1/10 ของ morphine); ส่วนหนึ่งถูกเปลี่ยนเป็น morphine ที่ตับ",
  "brandNamesTh": [
    "Codeine phosphate"
  ],
  "indications": [
    {
      "text": "ระงับอาการไอแห้งไม่มีเสมหะ (kennel cough, tracheal collapse) และความปวดเบา-ปานกลาง ในสุนัข; ⚠️ ไม่ค่อยใช้ในแมว (แมวไวต่อ morphine-like)",
      "cites": [
        "petplace-codeine",
        "merck-antitussive-u"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "เป็นยาควบคุม (opioid); ห้าม/ระวังในไอมีเสมหะ (กดการขับเสมหะ); ท้องผูก ซึม กดการหายใจ (ขนาดสูง); ⚠️ ระวังในแมว; เลี่ยงสูตรผสม acetaminophen ในแมว (พิษร้ายแรง)",
      "cites": [
        "petplace-codeine",
        "merck-antitussive-u"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "ท้องผูก ซึม คลื่นไส้, กดการหายใจ (ขนาดสูง); สูตรผสม acetaminophen = ห้ามในแมว",
      "cites": [
        "petplace-codeine"
      ]
    }
  ],
  "dosages": [
    {
      "species": "canine",
      "indication": "Antitussive / mild analgesia",
      "route": "PO",
      "dose": "1–2 mg/kg PO ทุก 6–12 ชั่วโมง",
      "cites": [
        "petplace-codeine",
        "merck-antitussive-u"
      ]
    }
  ],
  "citations": [
    {
      "id": "petplace-codeine",
      "type": "monograph",
      "title": "Codeine for Dogs and Cats — PetPlace",
      "url": "https://www.petplace.com/article/drug-library/drug-library/library/codeine-for-dogs-and-cats",
      "year": 2025,
      "note": "Clinical veterinary drug reference.",
      "cid": null
    },
    {
      "id": "merck-antitussive-u",
      "type": "textbook",
      "title": "Antitussive Drugs in Animals — MSD/Merck Veterinary Manual",
      "year": 2025,
      "url": "https://www.merckvetmanual.com/pharmacology/systemic-pharmacotherapeutics-of-the-respiratory-system/antitussive-drugs-in-animals",
      "note": "Authoritative veterinary pharmacology reference. Copyrighted, cited not mirrored.",
      "cid": null
    },
    {
      "id": "wikipedia-codeine",
      "type": "monograph",
      "title": "Codeine — Wikipedia",
      "year": 2026,
      "url": "https://en.wikipedia.org/wiki/Codeine",
      "note": "Tertiary cross-check for class + mechanism. CC BY-SA 4.0. Not sole authority.",
      "cid": null
    }
  ],
  "mirroredFrom": [
    {
      "id": "who-atc",
      "name": "WHO ATC/DDD Index",
      "url": "https://www.whocc.no/atc_ddd_index/",
      "asOfDate": "2026-05-31",
      "license": "WHO publication, free for use with attribution"
    }
  ],
  "mirrorCIDs": [],
  "codes": {
    "atc": {
      "code": "R05DA04",
      "name": "Codeine",
      "level": 5
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-05-31",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-05-31",
  "version": 1,
  "changelog": [
    {
      "version": 1,
      "date": "2026-05-31",
      "summary": "New entry — clinical content compiled from cited authoritative sources (Merck Veterinary Manual / VCA / Today's Vet Practice / PetPlace / peer-reviewed), cross-checked. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

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