Verify Clindamycin

Drug JSON

This is exactly what your browser canonicalizes + SHA-256-hashes

{
  "slug": "clindamycin",
  "nameEn": "Clindamycin",
  "nameTh": "คลินดาไมซิน",
  "class": "Antibiotic — lincosamide (bacteriostatic)",
  "mechanism": "ยาปฏิชีวนะกลุ่ม lincosamide ยับยั้งการสร้างโปรตีนโดยจับ 50S ribosomal subunit; ออกฤทธิ์ดีต่อ gram-positive, anaerobe และ Toxoplasma; ซึมเข้ากระดูกและฟันได้ดี",
  "brandNamesTh": [
    "Antirobe",
    "Cleocin",
    "Clindabactin"
  ],
  "indications": [
    {
      "text": "ติดเชื้อ gram-positive และ anaerobe เช่น ฝีหนอง โรคปริทันต์ (periodontal) การติดเชื้อกระดูก (osteomyelitis); ใช้รักษา toxoplasmosis ในแมว",
      "cites": [
        "dailymed-clindamycin",
        "who-eml-22"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "ห้ามใช้ในสัตว์ที่แพ้ lincosamide; ระวังในสัตว์ที่มีโรคตับหรือไตบกพร่อง",
      "cites": [
        "dailymed-clindamycin"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "อาเจียน ท้องเสีย; ในแมวการป้อนยาเม็ดแบบแห้งอาจทำให้หลอดอาหารบาดเจ็บ จึงควรป้อนตามด้วยน้ำหรืออาหาร",
      "cites": [
        "dailymed-clindamycin"
      ]
    }
  ],
  "dosages": [
    {
      "species": "canine",
      "indication": "Soft-tissue / dental / bone infection",
      "route": "PO",
      "dose": "11 mg/kg ทุก 12 ชั่วโมง หรือ 22 mg/kg ทุก 24 ชั่วโมง",
      "cites": [
        "dailymed-clindamycin"
      ]
    },
    {
      "species": "feline",
      "indication": "Soft-tissue infection / toxoplasmosis",
      "route": "PO",
      "dose": "11–33 mg/kg ต่อวัน (ปรับตามความรุนแรง)",
      "cites": [
        "dailymed-clindamycin"
      ]
    }
  ],
  "citations": [
    {
      "id": "wikipedia-Clindamycin",
      "type": "monograph",
      "title": "Clindamycin — Wikipedia",
      "year": 2026,
      "url": "https://en.wikipedia.org/wiki/Clindamycin",
      "note": "Tertiary cross-check for class, mechanism, brand names. CC BY-SA 4.0. Not sole authority for any clinical claim.",
      "cid": null
    },
    {
      "id": "dailymed-clindamycin",
      "type": "regulatory-database",
      "title": "Clindamycin — NLM DailyMed (FDA Structured Product Labeling)",
      "year": 2025,
      "url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=clindamycin",
      "note": "Cross-checked source: FDA-approved labeling. Search by name returns relevant product labelings.",
      "cid": "2d88cc82cf22fdb0803edca0c58dc373e505b0d952c6c4cf9a67e8e9962244c9"
    },
    {
      "id": "atc-J01FF01",
      "type": "guideline",
      "title": "ATC J01FF01 — Clindamycin",
      "year": 2025,
      "url": "https://www.whocc.no/atc_ddd_index/?code=J01FF01&showdescription=no",
      "note": "Cross-checked source: WHO Collaborating Centre ATC/DDD index. Authoritative drug classification.",
      "cid": "c3e56c0db6011125691a623c7a380a50efffec4a70c838a87ae2a876817d014f"
    },
    {
      "id": "pubchem-clindamycin",
      "type": "monograph",
      "title": "Clindamycin — PubChem search",
      "year": 2025,
      "url": "https://pubchem.ncbi.nlm.nih.gov/#query=Clindamycin",
      "note": "Cross-checked source: chemical structure, identifiers, pharmacology summary. Faculty review fills exact CID.",
      "cid": "7856dff2a630704353fb17c14483d7da3cf392a8bcc05b0e866bae13e2775820"
    },
    {
      "id": "who-eml-22",
      "type": "guideline",
      "title": "WHO Model List of Essential Medicines (22nd List, 2021)",
      "year": 2021,
      "url": "https://www.who.int/publications/i/item/WHO-MHP-HPS-EML-2021.02",
      "note": "Cross-checked source: drug appears on WHO EML — WHO recognizes its place in basic healthcare.",
      "cid": "71030c795c4e0c0cff56566bfc9ae4ed448eab9188ae68ce773a50d9f7fc53eb"
    },
    {
      "id": "wsava-amr-2023",
      "type": "guideline",
      "title": "WSAVA Therapeutic Guidelines Group — Library on Responsible Antimicrobial Use and AMR Prevention (2023)",
      "year": 2023,
      "url": "https://wsava.org/wp-content/uploads/2023/05/WSAVA-TGG-library-on-responsible-antimicrobial-use-and-AMR-prevention-2.pdf",
      "note": "Cross-checked source: WSAVA TGG framework for prudent antibiotic use in companion animals (PDF, stable URL).",
      "cid": "29f7ea6edf16004626349e036f3eb2ea30803ca1f6efd437bff0e8a4f2f465f1"
    }
  ],
  "mirroredFrom": [
    {
      "id": "dailymed",
      "name": "NLM DailyMed",
      "url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=clindamycin",
      "asOfDate": "2026-05-27",
      "license": "U.S. Government work — public domain. Attribution recommended."
    },
    {
      "id": "atc",
      "name": "WHO ATC Classification",
      "url": "https://www.whocc.no/atc_ddd_index/?code=J01FF01&showdescription=no",
      "asOfDate": "2026-05-27",
      "license": "WHO publication, free for use with attribution"
    },
    {
      "id": "pubchem",
      "name": "PubChem (NIH/NLM)",
      "url": "https://pubchem.ncbi.nlm.nih.gov/#query=Clindamycin",
      "asOfDate": "2026-05-27",
      "license": "NIH/NLM public domain"
    },
    {
      "id": "who-eml",
      "name": "WHO Model List of Essential Medicines (22nd List, 2021)",
      "url": "https://www.who.int/publications/i/item/WHO-MHP-HPS-EML-2021.02",
      "asOfDate": "2026-05-27",
      "license": "CC BY-NC-SA 3.0 IGO"
    },
    {
      "id": "wsava-amr",
      "name": "WSAVA TGG — Key Documents on Responsible Antimicrobial Use and AMR Prevention",
      "url": "https://wsava.org/wp-content/uploads/2023/05/WSAVA-TGG-library-on-responsible-antimicrobial-use-and-AMR-prevention-2.pdf",
      "asOfDate": "2026-05-27",
      "license": "Free for educational use with attribution"
    }
  ],
  "mirrorCIDs": [
    {
      "sourceId": "dailymed",
      "cid": "2d88cc82cf22fdb0803edca0c58dc373e505b0d952c6c4cf9a67e8e9962244c9",
      "capturedAt": "2026-05-27",
      "status": "stub"
    },
    {
      "sourceId": "atc",
      "cid": "c3e56c0db6011125691a623c7a380a50efffec4a70c838a87ae2a876817d014f",
      "capturedAt": "2026-05-27",
      "status": "stub"
    },
    {
      "sourceId": "pubchem",
      "cid": "7856dff2a630704353fb17c14483d7da3cf392a8bcc05b0e866bae13e2775820",
      "capturedAt": "2026-05-27",
      "status": "stub"
    },
    {
      "sourceId": "who-eml",
      "cid": "71030c795c4e0c0cff56566bfc9ae4ed448eab9188ae68ce773a50d9f7fc53eb",
      "capturedAt": "2026-05-27",
      "status": "stub"
    },
    {
      "sourceId": "wsava-amr",
      "cid": "29f7ea6edf16004626349e036f3eb2ea30803ca1f6efd437bff0e8a4f2f465f1",
      "capturedAt": "2026-05-27",
      "status": "stub"
    }
  ],
  "codes": {
    "atc": {
      "code": "J01FF01",
      "name": "Clindamycin",
      "level": 5
    },
    "rxnorm": {
      "cui": "2582",
      "name": "Clindamycin"
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-05-27",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-05-27",
  "version": 1,
  "changelog": [
    {
      "version": 0,
      "date": "2026-05-27",
      "summary": "Seed entry — cross-checked from 5 authoritative sources (NLM DailyMed, WHO ATC Classification, PubChem (NIH/NLM), WHO Model List of Essential Medicines (22nd List, 2021), WSAVA TGG — Key Documents on Responsible Antimicrobial Use and AMR Prevention). ATC J01FF01 + RxNorm 2582. Thai translation + faculty review pending."
    },
    {
      "version": 1,
      "date": "2026-05-27",
      "summary": "Clinical content compiled from cited sources — dog 11 mg/kg q12h or 22 mg/kg q24h, cat 11–33 mg/kg/day verified against FDA Antirobe (DailyMed) label. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

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