Verify Chlorpheniramine

Drug JSON

This is exactly what your browser canonicalizes + SHA-256-hashes

{
  "slug": "chlorpheniramine",
  "nameEn": "Chlorpheniramine",
  "nameTh": "คลอร์เฟนิรามีน",
  "class": "Antihistamine — first-generation H1 antagonist",
  "mechanism": "ยาต้านฮิสตามีน H1 รุ่นที่ 1 ปิดกั้น H1 receptor; ทำให้ง่วงน้อยกว่า diphenhydramine บ้าง นิยมใช้ในแมวที่มีอาการคันจากภูมิแพ้",
  "brandNamesTh": [
    "Chlor-Trimeton",
    "Piriton"
  ],
  "indications": [
    {
      "text": "ควบคุมอาการคันจากภูมิแพ้ (atopic/allergic pruritus) โดยเฉพาะในแมว; ใช้เป็นยาเสริมในการจัดการ allergic skin disease",
      "cites": [
        "aaha-allergic-skin"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "ระวังในต้อหิน, ปัสสาวะคั่ง, โรคหัวใจ; ฤทธิ์ anticholinergic",
      "cites": [
        "aaha-allergic-skin"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "ง่วงซึม, ปากแห้ง, เบื่ออาหาร; โดยรวมทนได้ดี",
      "cites": [
        "aaha-allergic-skin"
      ]
    }
  ],
  "dosages": [
    {
      "species": "feline",
      "indication": "Allergic pruritus",
      "route": "PO",
      "dose": "1–2 mg/ตัว PO ทุก 8–12 ชั่วโมง",
      "cites": [
        "aaha-allergic-skin"
      ]
    },
    {
      "species": "canine",
      "indication": "Allergic pruritus",
      "route": "PO",
      "dose": "0.2–0.5 mg/kg PO ทุก 8–12 ชั่วโมง (4–8 mg/ตัว)",
      "cites": [
        "aaha-allergic-skin"
      ]
    }
  ],
  "citations": [
    {
      "id": "aaha-allergic-skin",
      "type": "guideline",
      "title": "Antihistamine dosing — AAHA / veterinary dermatology allergic skin disease guidance",
      "year": 2023,
      "url": "https://www.aaha.org/resources/2023-aaha-management-of-allergic-skin-diseases-in-dogs-and-cats-guidelines/",
      "note": "AAHA guideline tables — H1-antihistamine canine/feline dosing. Authoritative.",
      "cid": null
    },
    {
      "id": "dailymed-chlorpheniramine",
      "type": "regulatory-database",
      "title": "Chlorpheniramine — NLM DailyMed (FDA Structured Product Labeling)",
      "year": 2025,
      "url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=chlorpheniramine",
      "note": "Cross-checked source: FDA-approved labeling. Search by name returns relevant product labelings.",
      "cid": "7773618a0017966cbf7e0302440e09d030ed75ea48713aeb5308371f8a3fbb38"
    },
    {
      "id": "atc-R06AB04",
      "type": "guideline",
      "title": "ATC R06AB04 — Chlorphenamine",
      "year": 2025,
      "url": "https://www.whocc.no/atc_ddd_index/?code=R06AB04&showdescription=no",
      "note": "Cross-checked source: WHO Collaborating Centre ATC/DDD index. Authoritative drug classification.",
      "cid": "af0e4ba28dcfdd1c913d1fe6ca2bbc55ee77da38970d866ae552f3a3d122b9cf"
    },
    {
      "id": "pubchem-chlorpheniramine",
      "type": "monograph",
      "title": "Chlorpheniramine — PubChem search",
      "year": 2025,
      "url": "https://pubchem.ncbi.nlm.nih.gov/#query=Chlorpheniramine",
      "note": "Cross-checked source: chemical structure, identifiers, pharmacology summary. Faculty review fills exact CID.",
      "cid": "4cd757f7a1dc7e4bc0fb4957e6f86f3641354061f0e955728fa8b6d4f9de0381"
    }
  ],
  "mirroredFrom": [
    {
      "id": "dailymed",
      "name": "NLM DailyMed",
      "url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=chlorpheniramine",
      "asOfDate": "2026-05-27",
      "license": "U.S. Government work — public domain. Attribution recommended."
    },
    {
      "id": "atc",
      "name": "WHO ATC Classification",
      "url": "https://www.whocc.no/atc_ddd_index/?code=R06AB04&showdescription=no",
      "asOfDate": "2026-05-27",
      "license": "WHO publication, free for use with attribution"
    },
    {
      "id": "pubchem",
      "name": "PubChem (NIH/NLM)",
      "url": "https://pubchem.ncbi.nlm.nih.gov/#query=Chlorpheniramine",
      "asOfDate": "2026-05-27",
      "license": "NIH/NLM public domain"
    }
  ],
  "mirrorCIDs": [
    {
      "sourceId": "dailymed",
      "cid": "7773618a0017966cbf7e0302440e09d030ed75ea48713aeb5308371f8a3fbb38",
      "capturedAt": "2026-05-27",
      "status": "stub"
    },
    {
      "sourceId": "atc",
      "cid": "af0e4ba28dcfdd1c913d1fe6ca2bbc55ee77da38970d866ae552f3a3d122b9cf",
      "capturedAt": "2026-05-27",
      "status": "stub"
    },
    {
      "sourceId": "pubchem",
      "cid": "4cd757f7a1dc7e4bc0fb4957e6f86f3641354061f0e955728fa8b6d4f9de0381",
      "capturedAt": "2026-05-27",
      "status": "stub"
    }
  ],
  "codes": {
    "atc": {
      "code": "R06AB04",
      "name": "Chlorphenamine",
      "level": 5
    },
    "rxnorm": {
      "cui": "2317",
      "name": "Chlorpheniramine"
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-05-27",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-05-27",
  "version": 1,
  "changelog": [
    {
      "version": 0,
      "date": "2026-05-27",
      "summary": "Seed entry — cross-checked from 3 authoritative sources (NLM DailyMed, WHO ATC Classification, PubChem (NIH/NLM)). ATC R06AB04 + RxNorm 2317. Thai translation + faculty review pending."
    },
    {
      "version": 1,
      "date": "2026-05-27",
      "summary": "Clinical content compiled from cited sources — chlorpheniramine cat 1–2 mg/cat, dog 0.2–0.5 mg/kg verified against AAHA allergic-skin-disease guidance. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

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