Verify Cefpodoxime proxetil

Drug JSON

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{
  "slug": "cefpodoxime",
  "nameEn": "Cefpodoxime proxetil",
  "nameTh": "เซฟโพดอกซิม",
  "class": "Antibiotic — third-generation cephalosporin (once-daily, oral)",
  "mechanism": "ยาปฏิชีวนะ β-lactam กลุ่ม cephalosporin รุ่นที่ 3 ชนิดกิน ยับยั้งการสร้างผนังเซลล์; ครอบคลุม gram-positive (Staphylococcus) และ gram-negative กว้างกว่ารุ่นที่ 1; ให้วันละครั้ง",
  "brandNamesTh": [
    "Simplicef",
    "Vantin"
  ],
  "indications": [
    {
      "text": "การติดเชื้อผิวหนังและเนื้อเยื่ออ่อน (pyoderma, wound) ในสุนัข ที่เกิดจาก Staphylococcus pseudintermedius และ gram-negative ที่ไว; ข้อดีคือให้วันละครั้ง compliance ดี",
      "cites": [
        "petplace-cefpodoxime",
        "vin-cefpodoxime"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "ห้ามใช้ในสัตว์ที่แพ้ cephalosporin; ระวัง cross-reactivity ในสัตว์ที่แพ้ penicillin",
      "cites": [
        "vin-cefpodoxime"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "GI upset (อาเจียน ท้องเสีย เบื่ออาหาร); ปฏิกิริยาภูมิแพ้พบน้อย",
      "cites": [
        "petplace-cefpodoxime"
      ]
    }
  ],
  "dosages": [
    {
      "species": "canine",
      "indication": "Skin / soft-tissue infection (pyoderma)",
      "route": "PO",
      "dose": "5–10 mg/kg PO วันละครั้ง",
      "cites": [
        "petplace-cefpodoxime",
        "vin-cefpodoxime"
      ]
    }
  ],
  "citations": [
    {
      "id": "petplace-cefpodoxime",
      "type": "monograph",
      "title": "Cefpodoxime Proxetil (Simplicef) for Dogs — PetPlace",
      "url": "https://www.petplace.com/article/drug-library/drug-library/library/cefpodoxime-proxetil-simplicef-for-dogs",
      "year": 2025,
      "note": "Clinical veterinary drug reference.",
      "cid": null
    },
    {
      "id": "vin-cefpodoxime",
      "type": "guideline",
      "title": "Cefpodoxime — Veterinary Partner (VIN)",
      "url": "https://veterinarypartner.vin.com/doc/?id=4951528",
      "year": 2025,
      "note": "Clinical veterinary drug reference.",
      "cid": null
    },
    {
      "id": "wikipedia-cefpodoxime",
      "type": "monograph",
      "title": "Cefpodoxime — Wikipedia",
      "year": 2026,
      "url": "https://en.wikipedia.org/wiki/Cefpodoxime",
      "note": "Tertiary cross-check for class + mechanism. CC BY-SA 4.0. Not sole authority.",
      "cid": null
    }
  ],
  "mirroredFrom": [
    {
      "id": "who-atc",
      "name": "WHO ATC/DDD Index",
      "url": "https://www.whocc.no/atc_ddd_index/",
      "asOfDate": "2026-05-30",
      "license": "WHO publication, free for use with attribution"
    }
  ],
  "mirrorCIDs": [],
  "codes": {
    "atc": {
      "code": "J01DD64",
      "name": "Cefpodoxime proxetil",
      "level": 5
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-05-30",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-05-30",
  "version": 1,
  "changelog": [
    {
      "version": 1,
      "date": "2026-05-30",
      "summary": "New entry — clinical content compiled from cited authoritative sources (Merck Veterinary Manual / VIN / PetPlace / Today's Vet Practice / peer-reviewed), cross-checked. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

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