Verify Buspirone

Drug JSON

This is exactly what your browser canonicalizes + SHA-256-hashes

{
  "slug": "buspirone",
  "nameEn": "Buspirone",
  "nameTh": "บัสไพโรน",
  "class": "Sedative — azapirone anxiolytic (5-HT1A partial agonist)",
  "mechanism": "azapirone anxiolytic — partial agonist ที่ serotonin 5-HT1A receptor ปรับสมดุล serotonin-dopamine ให้คลายกังวลโดยไม่กดประสาท/ไม่ทำให้ติด (ต่างจาก benzodiazepine); ออกฤทธิ์ช้า (~1 สัปดาห์)",
  "brandNamesTh": [
    "BuSpar",
    "Buspirone"
  ],
  "indications": [
    {
      "text": "ความวิตกกังวลเรื้อรัง, social anxiety, ความกลัวอ่อน-ปานกลาง, urine marking (แมว) ในสุนัขและแมว — ไม่กดประสาท/ไม่ disinhibition แบบ benzodiazepine",
      "cites": [
        "petplace-buspirone",
        "veteriankey-serotonergic"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "ออกฤทธิ์ช้า (~1 สัปดาห์) ไม่เหมาะกับความเครียดเฉียบพลัน/ตามสถานการณ์; ห้ามใช้ร่วม MAOI/serotonergic เกิน (serotonin syndrome); ระวังในตับ/ไตบกพร่อง",
      "cites": [
        "petplace-buspirone"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "โดยรวมทนได้ดี (ไม่กดประสาท); บางตัวกระสับกระส่าย/GI upset; แมวบางตัวเป็นมิตรมากขึ้นหรือก้าวร้าวขึ้น",
      "cites": [
        "petplace-buspirone"
      ]
    }
  ],
  "dosages": [
    {
      "species": "canine",
      "indication": "Chronic anxiety / fear",
      "route": "PO",
      "dose": "0.5–2 mg/kg PO ทุก 8–12 ชั่วโมง (ออกฤทธิ์เต็มที่ ~1–6 สัปดาห์)",
      "cites": [
        "petplace-buspirone",
        "veteriankey-serotonergic"
      ]
    },
    {
      "species": "feline",
      "indication": "Anxiety / urine marking",
      "route": "PO",
      "dose": "2.5–7.5 mg/ตัว PO วันละ 2–3 ครั้ง",
      "cites": [
        "petplace-buspirone"
      ]
    }
  ],
  "citations": [
    {
      "id": "petplace-buspirone",
      "type": "monograph",
      "title": "Buspirone HCl (BuSpar) for Dogs and Cats — PetPlace",
      "url": "https://www.petplace.com/article/drug-library/drug-library/library/buspirone-hcl-buspar-for-dogs-and-cats",
      "year": 2025,
      "note": "Clinical veterinary drug reference.",
      "cid": null
    },
    {
      "id": "veteriankey-serotonergic",
      "type": "guideline",
      "title": "Miscellaneous Serotonergic Agents (buspirone) — Veterian Key",
      "url": "https://veteriankey.com/miscellaneous-serotonergic-agents/",
      "year": 2025,
      "note": "Clinical veterinary drug reference.",
      "cid": null
    },
    {
      "id": "wikipedia-buspirone",
      "type": "monograph",
      "title": "Buspirone — Wikipedia",
      "year": 2026,
      "url": "https://en.wikipedia.org/wiki/Buspirone",
      "note": "Tertiary cross-check for class + mechanism. CC BY-SA 4.0. Not sole authority.",
      "cid": null
    }
  ],
  "mirroredFrom": [
    {
      "id": "who-atc",
      "name": "WHO ATC/DDD Index",
      "url": "https://www.whocc.no/atc_ddd_index/",
      "asOfDate": "2026-05-31",
      "license": "WHO publication, free for use with attribution"
    }
  ],
  "mirrorCIDs": [],
  "codes": {
    "atc": {
      "code": "N05BE01",
      "name": "Buspirone",
      "level": 5
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-05-31",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-05-31",
  "version": 1,
  "changelog": [
    {
      "version": 1,
      "date": "2026-05-31",
      "summary": "New entry — clinical content compiled from cited authoritative sources (Merck Veterinary Manual / FDA-EMA labels / VCA / peer-reviewed), cross-checked. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

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