Verify Budesonide

Drug JSON

This is exactly what your browser canonicalizes + SHA-256-hashes

{
  "slug": "budesonide",
  "nameEn": "Budesonide",
  "nameTh": "บูเดโซไนด์",
  "class": "Intestinal — locally-acting corticosteroid (IBD)",
  "mechanism": "corticosteroid ที่ออกฤทธิ์ต้านการอักเสบเฉพาะที่ลำไส้แรง (potency ~15 เท่าของ prednisone) แต่ถูกตับทำลายเกือบหมดเมื่อผ่าน first-pass จึงมีผล systemic ต่ำ — ใช้กับ IBD",
  "brandNamesTh": [
    "Entocort",
    "Budesonide"
  ],
  "indications": [
    {
      "text": "inflammatory bowel disease (IBD) และ colitis ในสุนัขและแมว — โดยเฉพาะเมื่อ steroid ระบบให้ผลข้างเคียงมาก หรือดื้อ; ผล systemic ต่ำกว่า prednisolone",
      "cites": [
        "vca-budesonide",
        "paper-budesonide"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "แม้ผล systemic ต่ำ แต่ยังกด HPA axis ได้ (ไม่ใช่ steroid-free); ห้ามใช้ร่วม NSAID; ระวังในเบาหวาน/ติดเชื้อ; ไม่ใช่ first-line (สงวนเมื่อ pred ไม่เหมาะ); ค่อย ๆ ลดเมื่อหยุด",
      "cites": [
        "vca-budesonide",
        "paper-budesonide"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "ผล steroid systemic น้อยกว่า prednisolone แต่ยังเกิดได้ (PU/PD, กด HPA) เมื่อใช้นาน/ขนาดสูง",
      "cites": [
        "paper-budesonide"
      ]
    }
  ],
  "dosages": [
    {
      "species": "canine",
      "indication": "Inflammatory bowel disease",
      "route": "PO",
      "dose": "1–3 mg/ตัว PO วันละครั้ง (ตามขนาดตัว; สุนัขเล็ก/แมว 1 mg วันละครั้ง)",
      "cites": [
        "vca-budesonide",
        "paper-budesonide"
      ]
    },
    {
      "species": "feline",
      "indication": "Inflammatory bowel disease",
      "route": "PO",
      "dose": "1 mg/ตัว PO วันละครั้ง",
      "cites": [
        "vca-budesonide"
      ]
    }
  ],
  "citations": [
    {
      "id": "vca-budesonide",
      "type": "monograph",
      "title": "Budesonide — VCA Animal Hospitals",
      "url": "https://vcahospitals.com/know-your-pet/budesonide",
      "year": 2025,
      "note": "Clinical veterinary drug reference.",
      "cid": null
    },
    {
      "id": "paper-budesonide",
      "type": "paper",
      "title": "Plasma concentrations and therapeutic effects of budesonide in dogs with IBD (AJVR 2013)",
      "url": "https://avmajournals.avma.org/view/journals/ajvr/74/1/ajvr.74.1.78.xml",
      "year": 2023,
      "note": "Peer-reviewed canine budesonide IBD study.",
      "cid": null
    },
    {
      "id": "wikipedia-budesonide",
      "type": "monograph",
      "title": "Budesonide — Wikipedia",
      "year": 2026,
      "url": "https://en.wikipedia.org/wiki/Budesonide",
      "note": "Tertiary cross-check for class + mechanism. CC BY-SA 4.0. Not sole authority.",
      "cid": null
    }
  ],
  "mirroredFrom": [
    {
      "id": "who-atc",
      "name": "WHO ATC/DDD Index",
      "url": "https://www.whocc.no/atc_ddd_index/",
      "asOfDate": "2026-05-31",
      "license": "WHO publication, free for use with attribution"
    }
  ],
  "mirrorCIDs": [],
  "codes": {
    "atc": {
      "code": "A07EA06",
      "name": "Budesonide",
      "level": 5
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-05-31",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-05-31",
  "version": 1,
  "changelog": [
    {
      "version": 1,
      "date": "2026-05-31",
      "summary": "New entry — clinical content compiled from cited authoritative sources (Merck Veterinary Manual / FDA-EMA labels / VCA / peer-reviewed), cross-checked. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

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