Verify Bismuth subsalicylate

Drug JSON

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{
  "slug": "bismuth-subsalicylate",
  "nameEn": "Bismuth subsalicylate",
  "nameTh": "บิสมัท ซับซาลิไซเลต",
  "class": "Intestinal — antidiarrheal / GI protectant",
  "mechanism": "antidiarrheal/gastroprotectant — เคลือบเยื่อบุทางเดินอาหาร, จับสารพิษแบคทีเรีย, ลดการอักเสบ (salicylate) และมีฤทธิ์ต้านแบคทีเรียอ่อน ๆ; ใช้กับท้องเสียและ gastritis ระยะสั้น",
  "brandNamesTh": [
    "Pepto-Bismol",
    "Bismuth"
  ],
  "indications": [
    {
      "text": "ท้องเสียเฉียบพลันและ gastritis ระยะสั้นในสุนัข (เคลือบ/จับสารพิษ); เคยใช้เสริมในโปรโตคอล Helicobacter",
      "cites": [
        "petco-bismuth",
        "askavet-bismuth"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "⚠️ ห้ามในแมว (salicylate toxicity — แมวกำจัด salicylate ไม่ได้); ⚠️ ห้ามใช้ร่วม NSAID, ในแผล GI, ความผิดปกติการแข็งตัวของเลือด, สัตว์ตั้งท้อง/อายุน้อย; ใช้ไม่เกิน 1–2 วัน; ⚠️ ทำให้อุจจาระดำ (อาจสับสนกับ melena)",
      "cites": [
        "petco-bismuth",
        "askavet-bismuth"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "อุจจาระดำ/ลิ้นดำ (คาดได้), ท้องผูก; salicylate toxicity ในแมวหรือเมื่อใช้นาน/ขนาดสูง",
      "cites": [
        "askavet-bismuth"
      ]
    }
  ],
  "dosages": [
    {
      "species": "canine",
      "indication": "Acute diarrhea / gastritis (short-term)",
      "route": "PO",
      "dose": "0.25–2 mL/kg (สูตร 17.5 mg/mL) PO ทุก 6–8 ชั่วโมง ไม่เกิน 1–2 วัน — ⚠️ ห้ามในแมว",
      "cites": [
        "petco-bismuth",
        "askavet-bismuth"
      ]
    }
  ],
  "citations": [
    {
      "id": "petco-bismuth",
      "type": "monograph",
      "title": "Bismuth Subsalicylate for Dogs (never cats) — Petco / drug reference",
      "url": "https://www.petco.com/content/content-hub/home/MedicationPages/01/bismuth-subsalicylate.html",
      "year": 2025,
      "note": "Clinical veterinary drug reference.",
      "cid": null
    },
    {
      "id": "askavet-bismuth",
      "type": "guideline",
      "title": "Pepto-Bismol (bismuth subsalicylate) for canine GI upset — Ask A Vet",
      "url": "https://askavet.com/blogs/news/veterinary-2025-guide-pepto-bismol%C2%AE-bismuth-subsalicylate-for-canine-gi-upset-%F0%9F%90%B6",
      "year": 2025,
      "note": "Clinical veterinary drug reference.",
      "cid": null
    },
    {
      "id": "wikipedia-bismuth_subsalicylate",
      "type": "monograph",
      "title": "Bismuth subsalicylate — Wikipedia",
      "year": 2026,
      "url": "https://en.wikipedia.org/wiki/Bismuth_subsalicylate",
      "note": "Tertiary cross-check for class + mechanism. CC BY-SA 4.0. Not sole authority.",
      "cid": null
    }
  ],
  "mirroredFrom": [
    {
      "id": "who-atc",
      "name": "WHO ATC/DDD Index",
      "url": "https://www.whocc.no/atc_ddd_index/",
      "asOfDate": "2026-05-31",
      "license": "WHO publication, free for use with attribution"
    }
  ],
  "mirrorCIDs": [],
  "codes": {
    "atc": {
      "code": "A07BB",
      "name": "Bismuth preparations",
      "level": 4
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-05-31",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-05-31",
  "version": 1,
  "changelog": [
    {
      "version": 1,
      "date": "2026-05-31",
      "summary": "New entry — clinical content compiled from cited authoritative sources (Merck Veterinary Manual / VCA / Today's Vet Practice / PetPlace / peer-reviewed), cross-checked. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

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