Verify Apomorphine

Drug JSON

This is exactly what your browser canonicalizes + SHA-256-hashes

{
  "slug": "apomorphine",
  "nameEn": "Apomorphine",
  "nameTh": "อะโพมอร์ฟีน",
  "class": "Emetic — central dopamine agonist (canine decontamination)",
  "mechanism": "กระตุ้น dopamine receptor ที่ chemoreceptor trigger zone ทำให้อาเจียน; ใช้กระตุ้นอาเจียนในสุนัขที่กินสารพิษไม่นาน; ไม่ใช้ในแมว (ตอบสนองไม่ดี)",
  "brandNamesTh": [
    "Apomorphine"
  ],
  "indications": [
    {
      "text": "กระตุ้นอาเจียนในสุนัขที่กินสารพิษ/สิ่งแปลกปลอมภายในเวลาไม่นาน (เพื่อ decontamination); ⚠️ ไม่นิยมในแมว (ใช้ dexmedetomidine/xylazine แทน)",
      "cites": [
        "tvp-emetics",
        "merck-emetics"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "ห้ามกระตุ้นอาเจียนเมื่อกินสารกัดกร่อน (corrosive), ปิโตรเลียม, หรือสัตว์ที่ซึม/ชัก/สำลักได้ง่าย; ไม่ใช้ในแมว",
      "cites": [
        "tvp-emetics"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "อาเจียนนาน (protracted vomiting), ซึม, กดการหายใจที่ขนาดสูง; หากอาเจียนไม่หยุดให้ naloxone (แต่ไม่หยุด emesis)",
      "cites": [
        "tvp-emetics"
      ]
    }
  ],
  "dosages": [
    {
      "species": "canine",
      "indication": "Induced emesis (decontamination)",
      "route": "IV",
      "dose": "0.03–0.1 mg/kg IV (หรือ 0.1 mg/kg SC); รูปแบบเม็ดละลายใส่ถุงเยื่อบุตา (conjunctival) แล้วล้างออกเมื่ออาเจียน",
      "cites": [
        "tvp-emetics",
        "merck-emetics"
      ]
    }
  ],
  "citations": [
    {
      "id": "tvp-emetics",
      "type": "guideline",
      "title": "Emetics in Small Animals — Today's Veterinary Practice",
      "url": "https://todaysveterinarypractice.com/pharmacology/emetics-in-small-animals/",
      "year": 2024,
      "note": "Peer-reviewed veterinary clinical practice journal.",
      "cid": null
    },
    {
      "id": "merck-emetics",
      "type": "textbook",
      "title": "Drugs Used to Control or Stimulate Vomiting — MSD/Merck Veterinary Manual",
      "year": 2025,
      "url": "https://www.merckvetmanual.com/pharmacology/systemic-pharmacotherapeutics-of-the-digestive-system/drugs-used-to-control-or-stimulate-vomiting-in-monogastric-animals",
      "note": "Authoritative veterinary pharmacology reference. Copyrighted, cited not mirrored.",
      "cid": null
    },
    {
      "id": "wikipedia-Apomorphine",
      "type": "monograph",
      "title": "Apomorphine — Wikipedia",
      "year": 2026,
      "url": "https://en.wikipedia.org/wiki/Apomorphine",
      "note": "Tertiary cross-check for class + mechanism. CC BY-SA 4.0. Not sole authority.",
      "cid": null
    }
  ],
  "mirroredFrom": [
    {
      "id": "who-atc",
      "name": "WHO ATC/DDD Index",
      "url": "https://www.whocc.no/atc_ddd_index/",
      "asOfDate": "2026-05-27",
      "license": "WHO publication, free for use with attribution"
    }
  ],
  "mirrorCIDs": [],
  "codes": {
    "atc": {
      "code": "N04BC02",
      "name": "Apomorphine",
      "level": 5
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-05-27",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-05-27",
  "version": 1,
  "changelog": [
    {
      "version": 1,
      "date": "2026-05-27",
      "summary": "New entry — clinical content compiled from cited authoritative sources (RECOVER 2024 / BSAVA / Merck / AAHA / ACVIM / peer-reviewed), cross-checked. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

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