Verify Altrenogest

Drug JSON

This is exactly what your browser canonicalizes + SHA-256-hashes

{
  "slug": "altrenogest",
  "nameEn": "Altrenogest",
  "nameTh": "อัลทรีโนเจสต์",
  "class": "Reproductive — synthetic progestogen (oral)",
  "mechanism": "progestogen สังเคราะห์ชนิดกิน ออกฤทธิ์เหมือน progesterone กด GnRH/LH ระงับการเป็นสัด; ใช้คุมวงรอบการเป็นสัดในม้าและสุกรเป็นหลัก",
  "brandNamesTh": [
    "Regu-Mate",
    "Altren"
  ],
  "indications": [
    {
      "text": "ระงับการเป็นสัด (estrus suppression) ในม้า เพื่อให้กำหนดเวลาการเป็นสัดได้หลังหยุดยา; ซิงโครไนซ์การเป็นสัดในสุกร",
      "cites": [
        "fda-regumate",
        "merck-repro-overview-b"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "⚠️ ดูดซึมผ่านผิวหนังคน — ผู้ตั้งครรภ์/ผู้มีภาวะลิ่มเลือด/ผู้หญิงห้ามสัมผัส (สวมถุงมือ); ห้ามในม้าที่มี/เสี่ยงมดลูกอักเสบ; ใช้รูปกินตรงโคนลิ้นหรือผสมอาหาร",
      "cites": [
        "fda-regumate"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "โดยรวมทนได้ดีในม้า; ความเสี่ยงหลักคือการสัมผัสของผู้ให้ยา (human exposure)",
      "cites": [
        "fda-regumate"
      ]
    }
  ],
  "dosages": [
    {
      "species": "equine",
      "indication": "Estrus suppression (mare)",
      "route": "PO",
      "dose": "0.044 mg/kg PO วันละครั้ง นาน 15 วันติดต่อกัน (1 mL ต่อ 50 kg ของสารละลาย 2.2 mg/mL)",
      "cites": [
        "fda-regumate"
      ]
    }
  ],
  "citations": [
    {
      "id": "fda-regumate",
      "type": "package-insert",
      "title": "Regu-Mate (altrenogest) — Merck/FDA veterinary label",
      "year": 2025,
      "url": "https://www.merck-animal-health-usa.com/products/regu-mate/",
      "note": "FDA/EMA-approved veterinary product label. Public regulatory labeling.",
      "cid": null
    },
    {
      "id": "merck-repro-overview-b",
      "type": "textbook",
      "title": "Systemic Pharmacotherapeutics of the Reproductive System — MSD/Merck Veterinary Manual",
      "year": 2025,
      "url": "https://www.merckvetmanual.com/pharmacology/systemic-pharmacotherapeutics-of-the-reproductive-system/overview-of-systemic-pharmacotherapeutics-of-the-reproductive-system-in-animals",
      "note": "Authoritative veterinary pharmacology reference. Copyrighted, cited not mirrored.",
      "cid": null
    },
    {
      "id": "wikipedia-altrenogest",
      "type": "monograph",
      "title": "Altrenogest — Wikipedia",
      "year": 2026,
      "url": "https://en.wikipedia.org/wiki/Altrenogest",
      "note": "Tertiary cross-check for class + mechanism. CC BY-SA 4.0. Not sole authority.",
      "cid": null
    }
  ],
  "mirroredFrom": [
    {
      "id": "who-atc",
      "name": "WHO ATC/DDD Index",
      "url": "https://www.whocc.no/atc_ddd_index/",
      "asOfDate": "2026-05-31",
      "license": "WHO publication, free for use with attribution"
    }
  ],
  "mirrorCIDs": [],
  "codes": {
    "atc": {
      "code": "QG03DX90",
      "name": "Altrenogest (veterinary progestogen)",
      "level": 5
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-05-31",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-05-31",
  "version": 1,
  "changelog": [
    {
      "version": 1,
      "date": "2026-05-31",
      "summary": "New entry — clinical content compiled from cited authoritative sources (Merck Veterinary Manual / FDA-EMA labels / WSAVA / peer-reviewed), cross-checked. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

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