Verify Alprazolam

Drug JSON

This is exactly what your browser canonicalizes + SHA-256-hashes

{
  "slug": "alprazolam",
  "nameEn": "Alprazolam",
  "nameTh": "อัลพราโซแลม",
  "class": "Sedative — benzodiazepine (situational anxiety / panic)",
  "mechanism": "benzodiazepine ออกฤทธิ์สั้น-ปานกลาง เสริม GABA-A receptor ให้ความสงบ คลายกังวล คลายกล้ามเนื้อ; ออกฤทธิ์เร็วเหมาะใช้ตามสถานการณ์ (พายุ ดอกไม้ไฟ เดินทาง)",
  "brandNamesTh": [
    "Xanax"
  ],
  "indications": [
    {
      "text": "ความวิตกกังวลตามสถานการณ์ (noise phobia, storm/firework, การเดินทาง, แยกจากเจ้าของแบบเฉียบพลัน) ในสุนัขและแมว; ให้ก่อนเหตุการณ์ 30–60 นาที",
      "cites": [
        "vca-alprazolam",
        "overall-bzd"
      ]
    }
  ],
  "contraindications": [
    {
      "text": "ระวัง paradoxical excitation (อาจก้าวร้าวขึ้น), ตับบกพร่อง; เป็นยาควบคุม; อาจเกิด disinhibition — ทดสอบ trial dose ก่อนเหตุการณ์จริง",
      "cites": [
        "overall-bzd"
      ]
    }
  ],
  "sideEffects": [
    {
      "text": "ง่วงซึม เดินเซ, paradoxical excitement/disinhibition, เพิ่มความอยากอาหาร; dependence เมื่อใช้ต่อเนื่อง",
      "cites": [
        "vca-alprazolam"
      ]
    }
  ],
  "dosages": [
    {
      "species": "canine",
      "indication": "Situational anxiety / noise phobia",
      "route": "PO",
      "dose": "0.02–0.1 mg/kg PO ทุก 6–12 ชม. ตามต้องการ (ก่อนเหตุการณ์ 30–60 นาที)",
      "cites": [
        "vca-alprazolam",
        "overall-bzd"
      ]
    },
    {
      "species": "feline",
      "indication": "Situational anxiety",
      "route": "PO",
      "dose": "0.125–0.25 mg/ตัว PO ทุก 8–24 ชั่วโมง ตามต้องการ",
      "cites": [
        "vca-alprazolam"
      ]
    }
  ],
  "citations": [
    {
      "id": "vca-alprazolam",
      "type": "monograph",
      "title": "Alprazolam — VCA Animal Hospitals",
      "url": "https://vcahospitals.com/know-your-pet/alprazolam",
      "year": 2025,
      "note": "Clinical veterinary drug reference.",
      "cid": null
    },
    {
      "id": "overall-bzd",
      "type": "guideline",
      "title": "Generalized guidelines for using alprazolam and other benzodiazepines (Overall)",
      "url": "https://www.karenoverall.com/wp-content/uploads/2020/06/Generalized-guidelines-for-using-alprazolam-and-other-BZDs-for-distress_Overall.pdf",
      "year": 2025,
      "note": "Clinical veterinary drug reference.",
      "cid": null
    },
    {
      "id": "wikipedia-alprazolam",
      "type": "monograph",
      "title": "Alprazolam — Wikipedia",
      "year": 2026,
      "url": "https://en.wikipedia.org/wiki/Alprazolam",
      "note": "Tertiary cross-check for class + mechanism. CC BY-SA 4.0. Not sole authority.",
      "cid": null
    }
  ],
  "mirroredFrom": [
    {
      "id": "who-atc",
      "name": "WHO ATC/DDD Index",
      "url": "https://www.whocc.no/atc_ddd_index/",
      "asOfDate": "2026-05-30",
      "license": "WHO publication, free for use with attribution"
    }
  ],
  "mirrorCIDs": [],
  "codes": {
    "atc": {
      "code": "N05BA12",
      "name": "Alprazolam",
      "level": 5
    }
  },
  "drafting": {
    "aiAssisted": false,
    "aiModel": null,
    "aiPromptHash": null,
    "humanReviewer": "palmzamak2547",
    "humanReviewedAt": "2026-05-30",
    "humanEditsRatio": null
  },
  "signatures": [],
  "reviewedBy": null,
  "lastUpdated": "2026-05-30",
  "version": 1,
  "changelog": [
    {
      "version": 1,
      "date": "2026-05-30",
      "summary": "New entry — clinical content compiled from cited authoritative sources (Merck Veterinary Manual / FDA-EMA labels / VSSO / Today's Vet Practice / peer-reviewed), cross-checked. Every statement cited. Reviewed by palmzamak2547. Pending faculty canonical signature."
    }
  ]
}

Public keys used

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