Antibiotic — sulfonamide + DHFR inhibitor combination (broad-spectrum)

Trimethoprim-Sulfamethoxazole

ไตรเมโทพริม-ซัลฟาเมทอกซาโซล

ชื่อทางการค้า · Bactrim, Septra, Tribrissen, Co-trimoxazole

กลไกการออกฤทธิ์ · Mechanism

TEMPLATE — mechanism pending Thai translation + faculty review (cross-check DailyMed + WHO ATC + PubChem + WHO Essential Medicines List + WSAVA Antimicrobial Stewardship guidelines)

ข้อบ่งใช้ · Indications

TEMPLATE — indications pending Thai translation + faculty review (cross-check DailyMed + WHO ATC + PubChem + WHO Essential Medicines List + WSAVA Antimicrobial Stewardship guidelines)^{[1] [2] [3] [4] [5]}

ข้อห้ามใช้ · Contraindications

TEMPLATE — contraindications pending Thai translation + faculty review (cross-check DailyMed + WHO ATC + PubChem + WHO Essential Medicines List + WSAVA Antimicrobial Stewardship guidelines)^{[1] [2] [3] [4] [5]}

ขนาดยา · Dosage

Species	Indication	Route	Dose	Cite
canine	TEMPLATE — pending faculty review	PO	— TEMPLATE: รอ dose จาก peer-reviewed source + faculty signoff —	^{[1] [2] [3] [4] [5]}
feline	TEMPLATE — pending faculty review	PO	— TEMPLATE: รอ dose จาก peer-reviewed source + faculty signoff —	^{[1] [2] [3] [4] [5]}

ผลข้างเคียง · Side effects

TEMPLATE — side effects pending Thai translation + faculty review (cross-check DailyMed + WHO ATC + PubChem + WHO Essential Medicines List + WSAVA Antimicrobial Stewardship guidelines)^{[1] [2] [3] [4] [5]}

References

1regulatory-database · Trimethoprim-Sulfamethoxazole — NLM DailyMed (FDA Structured Product Labeling), 2025upstream ↗c/077dd26c…8637Cross-checked source: FDA-approved labeling. Search by name returns relevant product labelings.
2guideline · ATC J01EE01 — Trimethoprim and sulfamethoxazole (Co-trimoxazole), 2025upstream ↗c/ef5dee5e…02e2Cross-checked source: WHO Collaborating Centre ATC/DDD index. Authoritative drug classification.
3monograph · Trimethoprim-Sulfamethoxazole — PubChem search, 2025upstream ↗c/726b1a49…26b4Cross-checked source: chemical structure, identifiers, pharmacology summary. Faculty review fills exact CID.
4guideline · WHO Model List of Essential Medicines (22nd List, 2021), 2021upstream ↗c/71030c79…53ebCross-checked source: drug appears on WHO EML — WHO recognizes its place in basic healthcare.
5guideline · WSAVA Therapeutic Guidelines Group — Library on Responsible Antimicrobial Use and AMR Prevention (2023), 2023upstream ↗c/29f7ea6e…65f1Cross-checked source: WSAVA TGG framework for prudent antibiotic use in companion animals (PDF, stable URL).